Evidence map›Paper›PMID 41436104›Full record

ReviewJournal of oral & facial pain and headache2025

Olfactory abnormalities in patients with migraine: a narrative review of a symptom commonly overlooked by neurologists.

Dong-Xue Ren, Mao-Mei Song, Ying-Jie Gao, Chang-Xin Li, Sui-Yi Xu

Abstract readReview
In one paragraph

Review in Journal of oral & facial pain and headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong-Xue RenDepartment of Neurology, Headache Center, The First Hospital of Shanxi Medical University, 030001 Taiyuan, Shanxi, China.
Mao-Mei SongDepartment of Neurology, Headache Center, The First Hospital of Shanxi Medical University, 030001 Taiyuan, Shanxi, China.
Ying-Jie GaoDepartment of Neurology, Headache Center, The First Hospital of Shanxi Medical University, 030001 Taiyuan, Shanxi, China.
Chang-Xin LiDepartment of Neurology, Headache Center, The First Hospital of Shanxi Medical University, 030001 Taiyuan, Shanxi, China.
Sui-Yi XuDepartment of Neurology, Headache Center, The First Hospital of Shanxi Medical University, 030001 Taiyuan, Shanxi, China.ORCID 0000-0002-8908-011X

Funding

Shanxi Basic Research Program 202303021221222
6 · The paper itself

Abstract

Nausea, vomiting, photophobia, and phonophobia are common concomitant symptoms in patients with migraine and provide valuable information for headache specialists during consultations. Clinical observations have identified various olfactory abnormalities in patients with migraine, such as osmophobia, olfactory hallucinations, hyperosmia and hyposmia, which are often overlooked by neurologists. These olfactory abnormalities may interact with the trigeminal vascular system, parasympathetic nervous system, and cortical spreading depression. This review aimed to examine the mechanisms underlying olfactory abnormalities in patients with migraine and the clinical correlations between these abnormalities and migraine. Additionally, olfactory training is highlighted as a promising non-pharmacological treatment for migraine.

Indexed as

Migraine DisordersOlfaction DisordersHumansNeurologistsAnosmiaHyperosmiaHyposmiaMigraineOlfactory hallucinationsOsmophobia

Identifiers

PMID41436104
PMCPMC12727172

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.