Evidence map›Paper›PMID 41433209›Full record

ArticleORL; journal for oto-rhino-laryngology and its related specialties2025

Stimulating the Human Olfactory Bulb to Evoke Smell Perception: A Case Report from Awake Brain Surgery.

Coralie Mignot, Susanne Weise, Stephan B Sobottka, Moustafa Bensafi, Dino Podlesek, Thomas Hummel

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ORL; journal for oto-rhino-laryngology and its related specialties, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Coralie MignotSmell & Taste Clinic, Department of Otorhinolaryngology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany, coralie.mignot@ukdd.de.
Susanne WeiseSmell & Taste Clinic, Department of Otorhinolaryngology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Stephan B SobottkaDepartment of Neurosurgery, Technische Universität Dresden, Dresden, Germany.
Moustafa BensafiLyon Neuroscience Research Center, CNRS - INSERM - University Claude Bernard of Lyon, Lyon, France.
Dino PodlesekDepartment of Neurosurgery, Technische Universität Dresden, Dresden, Germany.
Thomas HummelSmell & Taste Clinic, Department of Otorhinolaryngology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Approximately one-third of patients with olfactory dysfunction would consider the option of an olfactory implant, a device that would sample odorants and translate this information into an electrical stimulation of the brain to produce an olfactory percept. However, the brain location for placement of such a device is to date still debated. Case Presentation: We describe the single-case of a patient with left-sided frontotemporal astrocytoma who reported perceiving a lemon smell after electrical stimulation in the olfactory bulb. Conclusion: The awake-brain surgery provides a unique opportunity to test how smell percepts are formed at the central level in humans. This information is critical in the emerging field of olfactory implants. The present case emphasizes the significant role of the olfactory bulb as a target structure for the placement of an olfactory prosthesis. </p>.

Indexed as

AstrocytomaBrain NeoplasmsElectric StimulationOlfaction DisordersOlfactory PerceptionFemaleHumansMaleMiddle AgedOlfactory BulbSmellWakefulnessAwake-brain surgeryCase reportOlfactionOlfactory bulbStimulation

Identifiers

PMID41433209
PMCPMC12880826

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.