Evidence map›Paper›PMID 41432817›Full record

SynthesisCurrent urology reports2025

Bladder Neck Incision in Posterior Urethral Valve Management: a Meta-Analysis with Insights into Adjunctive Bladder Interventions.

Mohamed Tharwat, Reham Ramadan, Abdelwahab Hashem, Diaa-Eldin Taha, Mohamed Hussiny, Ahmed Elkashef, Tamer E Helmy, Mohamed S Dawaba, Ashraf T Hafez

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Current urology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamed Tharwat *Urology Department, King Salman Armed Forces Hospital, Tabuk city, Kingdom of Saudi Arabia.
Reham Ramadan *Egyptian Ministry of Health, Dakahlia, Egypt.
Abdelwahab HashemUrology department, Faculty of medicine, Delta University for Science and Technology, Dakahlia, Egypt. abdelwahab.hashem@deltauniv.edu.eg.ORCID http://orcid.org/0000-0002-0664-3504
Diaa-Eldin TahaUrology department, Faculty of medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Mohamed HussinyPediatric Urology department, Urology and Nephrology Center, Mansoura, Egypt.
Ahmed ElkashefPediatric Urology department, Urology and Nephrology Center, Mansoura, Egypt.
Tamer E HelmyPediatric Urology department, Urology and Nephrology Center, Mansoura, Egypt.
Mohamed S DawabaPediatric Urology department, Urology and Nephrology Center, Mansoura, Egypt.
Ashraf T HafezPediatric Urology department, Urology and Nephrology Center, Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo evaluate the outcomes of bladder neck incision (BNI) and alternative treatments, such as alpha blockers, in improving voiding dysfunction in posterior urethral valve (PUV) after valve ablation (VA). RECENT

findingsEleven studies comprising 826 patients with PUV were included. Concomitant BNI and VA significantly improved both VUR resolution (Risk Ratio “RR”= 1.36; 95% CI: 1.04–1.79), and postoperative serum creatinine -0.16 (95% CI: -0.28 to -0.04). Concomitant BNI and VA significantly improved detrusor overactivity (RR = 0.44; 95% CI: 0.22–0.91; p = 0.03), and reduced significantly maximum detrusor pressure at Qmax (Pdetmax) by-23.53 (95% CI: -35.01 to -12.05). It also significantly decreased both the use of alpha blocker/anticholinergic (RR = 0.59; 95% CI: 0.36 to 0.95), and the need for intermittent catheterization (RR = 0.16; 95% CI: 0.03 to 0.83; p = 0.03). However, there were no significant difference either in bladder compliance (RR = 0.75; 95% CI: 0.31 to 1.79), nor children required re-intervention (RR = 0.52; 95% CI: 0.25 to 1.05). Alpha blockers after VA showed a pooled post-void residual urine reduction of -59.44 (95% CI: -129.05 to 10.17). The pooled estimate for peak flow rate with alpha blockers was 14.22 (95% CI: 13.70–14.74). BNI combined with valve ablation could improves bladder function and reduces the need for additional interventions compared to VA alone.

Indexed as

UrethraUrinary BladderHumansAlpha blockersPosterior urethral valveValve ablationVoiding dysfunction

Identifiers

PMID41432817
PMCPMC12727795

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.