Evidence map›Paper›PMID 41432800›Full record

ArticleTropical animal health and production2025

Effect of high growth rate in prepubertal age on hormonal and puberty status in crossbred (Angus x Nellore) heifers.

Marcos Vinicius de Castro Ferraz Junior, Marcelo Henrique Santos, Gabriela Baggio de Oliveira, Daniel Montanher Polizel, Guilherme de Paula Nogueira, Vinícius Nunes de Gouvêa, Janaina Socolovski Biava, Evandro Maia Ferreira, Nelma Pinheiro Fragata Beltrão, Alexandre Vaz Pires

Abstract read
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In one paragraph

Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcos Vinicius de Castro Ferraz JuniorDepartment of Animal Science, Federal University of Amazonas, Estrada Parintins Macurany, Jacareacanga, Parintins, AM, 69152240, Brazil. ferrazmvc@ufam.edu.br.ORCID http://orcid.org/0000-0002-6041-2539
Marcelo Henrique SantosDepartment of Nutrition and Animal Production, College of Veterinary and Animal Science, University of São Paulo, Duque de Caxias North Avenue, n 225, Pirassununga, SP, 13635-000, Brazil.
Gabriela Baggio de OliveiraDepartment of Nutrition and Animal Production, College of Veterinary and Animal Science, University of São Paulo, Duque de Caxias North Avenue, n 225, Pirassununga, SP, 13635-000, Brazil.
Daniel Montanher PolizelDepartment of Nutrition and Animal Production, College of Veterinary and Animal Science, University of São Paulo, Duque de Caxias North Avenue, n 225, Pirassununga, SP, 13635-000, Brazil.
Guilherme de Paula NogueiraSão Paulo State University (UNESP), Clovis Pestana 793, Araçatuba, SP, 16050-680, Brazil.
Vinícius Nunes de GouvêaTexas A&M AgriLife Research, Texas A&M University, Amarillo, TX, 79016, USA.
Janaina Socolovski BiavaDepartment of Animal Science, College of Agriculture "Luiz de Queiroz", University of São Paulo, Pádua Dias Avenue, n 11, PO Box 09, Piracicaba, SP, 13418-900, Brazil.
Evandro Maia FerreiraDepartment of Animal Science, College of Agriculture "Luiz de Queiroz", University of São Paulo, Pádua Dias Avenue, n 11, PO Box 09, Piracicaba, SP, 13418-900, Brazil.
Nelma Pinheiro Fragata BeltrãoDepartment of Animal Science, Federal University of Amazonas, Estrada Parintins Macurany, Jacareacanga, Parintins, AM, 69152240, Brazil.
Alexandre Vaz PiresDepartment of Nutrition and Animal Production, College of Veterinary and Animal Science, University of São Paulo, Duque de Caxias North Avenue, n 225, Pirassununga, SP, 13635-000, Brazil.

Funding

Fapesp Fapesp
6 · The paper itself

Abstract

This study evaluated whether accelerated growth during early development could hasten puberty in early-weaned Angus × Nellore heifers. Thirty-eight heifers (92 ± 2 kg BW; 3.0 ± 0.1 months of age) were randomly assigned to a 2 × 2 factorial design. Treatments consisted of high (H) or control (C) average daily gain (ADG) during Phase I (3–7 months; 1.0 vs. 0.5 kg/day) and Phase II (7 months to puberty; 0.9 vs. 0.6 kg/day), resulting in four groups (HH, HC, CH, CC). All heifers received the same diet, differing only in intake level (ad libitum or restricted to 50%). Puberty was determined by serum progesterone (P4 > 1.5 ng/mL) and follicular development was monitored by ultrasonography; blood samples were analyzed for leptin, insulin-like growth factor-1 (IGF-1), and luteinizing hormone (LH). High ADG in Phase I increased BW by 58 kg at 7 months. Puberty occurred earlier in HH, HC, and CH (12.4 ± 0.1 months) compared with CC (14.4 ± 0.4 months; P < 0.05). From 9 to 11 months, dominant follicle diameter was greater in HH, HC, and CH than in CC. Elevated leptin, IGF-1, and LH pulse frequency were also observed in heifers with accelerated early growth. Nevertheless, these endocrine changes were not sufficient to markedly advance puberty onset. In conclusion, nutritional strategies that enhance early growth improve body development and transient endocrine responses but do not significantly reduce the age at puberty in Angus × Nellore heifers.

Indexed as

Sexual MaturationAnimalsCattleDietFemaleInsulin-Like Growth Factor ILeptinLuteinizing HormoneOvarian FollicleProgesteroneWeight GainInsulin-Like Growth Factor ILeptinLuteinizing HormoneProgesteroneBeef cattleIGF-1LeptinLHNutrition

Identifiers

PMID41432800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.