Evidence map›Paper›PMID 41432728›Full record

ArticleClinical anatomy (New York, N.Y.)2026

A Novel Patient-Specific Landmark-Guided Approach for Intramuscular Botulinum Neurotoxin Injections Into the Rotator Cuff: A Cadaveric Study.

Dave Osinachukwu Duru, David Kwan Ryung Lee, Gavin E Jarvis, Niel Kang, Salma Chaudhury, Cecilia Brassett

Abstract read
In one paragraph

Article in Clinical anatomy (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dave Osinachukwu DuruHuman Anatomy Centre, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0009-0005-8396-6146
David Kwan Ryung LeeHuman Anatomy Centre, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Gavin E JarvisSchool of Medicine, University of Sunderland, Sunderland, UK.
Niel KangHuman Anatomy Centre, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Salma ChaudhuryHuman Anatomy Centre, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Cecilia BrassettHuman Anatomy Centre, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.

Funding

Royal College of Surgeons of England
6 · The paper itself

Abstract

Myofascial pain syndrome (MFPS) causes chronic shoulder pain. Supraspinatus and infraspinatus, rotator cuff muscles innervated by the suprascapular nerve, are commonly affected. Intramuscular botulinum neurotoxin (BoNT) injections near motor points (i.e., visible nerve branch entry sites used as a proxy for motor endplates) are an effective treatment for such pain. However, current techniques limit accessibility. This study aimed to develop a patient-specific, landmark-guided technique for BoNT delivery into supraspinatus and infraspinatus using scapular dimensions. Ten pairs of cadaveric shoulders (n = 20) were dissected to identify supraspinatus and infraspinatus motor points. Distances from scapular landmarks to these motor points were measured in two axes. These distances were correlated with scapular dimensions (height, spine length, width) using linear regression. Patient-specific predictive formulae were derived. For validation, landmark-guided methylene blue dye injections were performed on four additional shoulders using calculated coordinates. For supraspinatus, motor points were predicted using deltoid tubercle and root of the scapular spine (r = 0.58-0.64, p = 0.0016-0.021). For infraspinatus, root of the scapular spine and lateral acromion were used (r = 0.46-0.60, p = 0.0054-0.0500). In all validation specimens, injected dye accurately reached the motor points. This study provides a validated, patient-specific, landmark-guided technique for BoNT delivery into the rotator cuff, offering an approach for accessible analgesia.

Indexed as

Anatomic LandmarksBotulinum ToxinsRotator CuffAgedAged, 80 and overCadaverFemaleHumansInjections, IntramuscularMaleMiddle AgedScapulaBotulinum Toxinsbotulinum neurotoxin (BoNT)cadavericinjectionlandmark‐guidedmotor pointsmyofascial painpatient‐specificrotator cuffsuprascapular nervevariation

Identifiers

PMID41432728
PMCPMC13648302

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.