ReviewPhysiology (Bethesda, Md.)2026
Compartmentalized Nutrient and Hormone Sensing in β-Cells: the Role of Primary Cilia.
Review in Physiology (Bethesda, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
2 authors.
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Abstract
Pancreatic β-cells couple nutrient and hormone sensing to insulin release. Prevailing models depict the β-cell as a homogeneous metabolic unit, overlooking specialized subcellular compartments like the primary cilium. Primary cilia are sensory organelles that function as critical signaling hubs in pancreatic β-cells. Disrupting primary cilia causes diabetes, but the underlying mechanisms remain unclear. In this review, we critically assess evidence supporting the cilium's role in β-cells, including functional studies that implicate cilia in the control of cytosolic Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.