Evidence map›Paper›PMID 41432388›Full record

ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2026

Association of Radiologic Findings of Otosclerosis Using Photon-Counting Computed Tomography With Hearing.

Eric E Babajanian, John C Benson, Paul J Farnsworth, Hayden J Swartz, Shuai Leng, Christine M Lohse, Jack I Lane, Matthew L Carlson

Abstract read
In one paragraph

Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Photon-counting detector computed tomography for temporal bone: does higher resolution matter?Current opinion in otolaryngology & head and neck surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eric E BabajanianDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic.
John C BensonDepartment of Radiology, Mayo Clinic.
Paul J FarnsworthDepartment of Radiology, Mayo Clinic.
Hayden J SwartzDepartment of Radiology, Mayo Clinic.
Shuai LengDepartment of Radiology, Mayo Clinic.
Christine M LohseDepartment of Quantitative Health Sciences, Mayo Clinic.
Jack I LaneDepartment of Radiology, Mayo Clinic.
Matthew L CarlsonDepartment of Otolaryngology-Head and Neck Surgery, Mayo Clinic.

Funding

High-resolution in vivo imaging of inner ear using photon-counting-detector computed tomography and artificial intelligenceR01DC022228 · NIDCD · MAYO CLINIC ROCHESTER · PI Matthew L Carlson, Shuai Leng · 2025 to 2026
$1.5M
NIDCD NIH HHS R01 DC022228
6 · The paper itself

Abstract

objectiveTo examine the association of extent of otosclerotic plaque using high-resolution photon-counting computed tomography (PCCT) with hearing and surgical outcomes. STUDY

designHistorical cohort.

settingLarge academic center. PATIENTS: Patients with otosclerosis who completed PCCT imaging at time of initial evaluation.

interventionsObservation, surgery.

main outcome measuresAudiometric data.

resultsA total of 53 ears were eligible for study. The mean age at PCCT was 51 years (SD: 14). The mean extent of oval window otosclerotic plaque measured in radial degrees was 112 (SD: 65) and the mean otosclerotic depth was 1.6mm (SD: 0.6). The mean air-bone gap pure-tone average was 18 dB (SD: 12) and the mean Carhart degree was 9 dB (SD: 10). The radial degrees of oval window extent were not significantly associated with air-bone gap (correlation coefficient: 0.14; P =0.3) or Carhart degree (correlation coefficient: 0.04; P =0.8). Likewise, otosclerotic plaque depth was not significantly associated with air-bone gap (correlation coefficient: -0.19; P =0.2) or Carhart degree (correlation coefficient: -0.08; P =0.6). After PCCT, 22 ears underwent surgery. In this subset, oval window extent and plaque depth were not significantly associated with the postoperative changes in air-bone gap or high-frequency thresholds.

conclusionsDespite enhanced visualization of subtle abnormalities with PCCT imaging, the extent of oval window otosclerotic plaque, measured in angular degrees and depth, was not associated with hearing loss at time of initial evaluation or postoperative audiologic changes in patients with otosclerosis.

Indexed as

HearingOtosclerosisAdultAgedAudiometry, Pure-ToneCohort StudiesFemaleHumansMaleMiddle AgedTomography, X-Ray ComputedTreatment OutcomeAudiologyClinical outcomeComputed tomographyOtosclerosis

Identifiers

PMID41432388
PMCPMC13195680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.