Evidence map›Paper›PMID 41431988›Full record

ArticleJournal of the American Heart Association2026

Huaqing Ye, Hongwei Yue, Shujian Wei, Kaiyi Wang, Kehui Yang, Han Du, Wentao Sang, Jialin Guo, Jingwen Wang, Yunyun Guo and 4 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Huaqing Ye *Department of Emergency Medicine Qilu Hospital of Shandong University Jinan China.
Hongwei Yue *Department of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0002-1839-4699
Shujian Wei *Department of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0002-0896-6032
Kaiyi Wang *Department of Emergency Medicine Qilu Hospital of Shandong University Jinan China.
Kehui YangDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0001-5135-9839
Han DuDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0001-5516-3032
Wentao SangDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0002-2440-4486
Jialin GuoDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0002-7439-5506
Jingwen WangDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0009-0001-6163-0204
Yunyun GuoDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.
Cheng ZhangNational Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences Qilu Hospital of Shandong University Jinan China.ORCID 0000-0003-3672-6543
Sumei CuiDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0009-0004-7933-4800
Feng XuDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0002-4670-3727
Yuguo ChenDepartment of Emergency Medicine Qilu Hospital of Shandong University Jinan China.ORCID 0000-0001-9501-2546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe inactivating

methodsUsing

results

conclusionsOur study provides definitive experimental evidence that

Indexed as

Aldehyde Dehydrogenase, MitochondrialBlood PressureEndothelial CellsHeat-Shock ProteinsHypertensionNitric Oxide Synthase Type IIIAngiotensin IIAnimalsDisease Models, AnimalEndoplasmic Reticulum Chaperone BiPHumansMaleMiceMice, Inbred C57BLMice, KnockoutSignal TransductionAldehyde Dehydrogenase, MitochondrialALDH2 protein, humanALDH2 protein, mouseAngiotensin IIEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsHSPA5 protein, humanHspa5 protein, mouseNitric Oxide Synthase Type IIINos3 protein, mouseALDH2ALDH2 rs671blood pressureHSPA5PIEZO1

Identifiers

PMID41431988
PMCPMC12909009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.