Evidence map›Paper›PMID 41431777›Full record

ArticleJournal of neuromuscular diseases2026

Identification of myokines associated with the pathological stress response in the

Erynn E Johnson, Jacob Powers, James M Ervasti

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuromuscular diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erynn E JohnsonDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
Jacob PowersDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
James M ErvastiDepartment of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.

Funding

TRAINING PROGRAM IN MUSCLE RESEARCHT32AR007612 · NIAMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JAMES M ERVASTI, DAWN A LOWE · 2001 to 2026
$11.3M
CYTOSKELETAL INTERACTIONS OF DYSTROPHINR01AR042423 · NIAMS · UNIVERSITY OF WISCONSIN MADISON · PI ERVASTI, JAMES M · 1994 to 2025
$9.3M
Costamere Defects in Muscular DystrophiesR01AR049899 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI ERVASTI, JAMES M · 2005 to 2025
$8.2M
Training Grant: Functional Proteomics of AgingT32AG029796 · NIA · UNIVERSITY OF MINNESOTA · PI EDGAR A ARRIAGA, Douglas G Mashek · 2008 to 2026
$6.6M
A transformative next-generation Orbitrap Tribrid system for the UMN and Upper MidwestS10OD028717 · OD · UNIVERSITY OF MINNESOTA · PI GRIFFIN, TIMOTHY J. · 2020 to 2020
$1.2M
NIAMS NIH HHS R01 AR042423NIAMS NIH HHS R01 AR049899NIAMS NIH HHS T32 AR007612NIA NIH HHS T32 AG029796NIH HHS S10 OD028717
6 · The paper itself

Abstract

purposeSkeletal muscle constitutes 30-40% of total body mass and is now considered an endocrine organ, given its secretion of a variety proteins, metabolites, and cytokines. We have previously shown that the absence of dystrophin in skeletal muscle contributes to lethal systemic stress pathology in the MAJOR

findingsOur analysis demonstrated that skeletal muscle dystrophinopathy is associated with increased expression of numerous proteins in both intact

conclusionsOur current study informs on the skeletal muscle secretory profile in

Indexed as

Muscle, SkeletalMuscular Dystrophy, DuchenneMyokinesStress, PhysiologicalAnimalsDisease Models, AnimalDystrophinMaleMiceMice, Inbred C57BLMice, Inbred mdxMice, TransgenicProteomicsDystrophinMyokinesduchenne muscular dystrophymyokineproteomicsskeletal musclestress physiology

Identifiers

PMID41431777
PMCPMC13434947

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.