Evidence map›Paper›PMID 41431682›Full record

ArticleBrain & spine2025

Intraoperative ultrasound in spinal surgery for surgical tailoring and control - A single center case series.

Anton Früh, Lukas Depperich, Helen König, Ahmad Almahozi, Joan Alsolivany, Lars Wessels, Peter Vajkoczy, Nils Hecht

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predurotomy intraoperative ultrasound in intradural extramedullary spinal tumor surgery: agreement with preoperative magnetic resonance imaging and correlation with microsurgical findings.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anton FrühDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Lukas DepperichDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Helen KönigDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Ahmad AlmahoziDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Joan AlsolivanyDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Lars WesselsDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Peter VajkoczyDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Nils HechtDepartment of Neurosurgery, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Intraoperative ultrasound (IOUS) has gained recognition as a valuable imaging modality for enhancing surgical precision in neurosurgical procedures. However, its routine clinical integration in spine surgery remains limited. Research question: This study aims to elucidate role of intraoperative ultrasound (IOUS) in spinal surgery and to propose the Spinal Cord Pulsatility Index (SCPI) as a novel, ultrasound-based parameter for evaluating spinal cord decompression. Material and methods: This retrospective single-center case series included all consecutive patients who underwent spinal surgery with IOUS guidance between June 2024 and January 2025. In a subset of patients undergoing posterior decompression, the SCPI - defined as the ratio between the spinal cord pulsation and the corresponding heart rate - was calculated. Results: Overall, IOUS was performed in 28 patients, and 3 main IOUS applications were determined: (1) anatomic localization, (2) augmentive use, and (3) spinal cord decompression assessment. Importantly, IOUS was fast and technically feasible in all cases, across regions of the spine and regardless of the surgical approach. In a subset of n = 8 cases, we noted a significant SCPI increase at the time-point of final decompression (*p < 0.05). Discussion and conclusion: IOUS in spinal surgery serves as a simple, safe, cost-effective, and non-invasive imaging modality for real-time localization of intradural and intramedullary pathologies and supplementary neurovascular structures. Based on the principle of communicating fluid dynamics, the spinal cord pulsation index may serve as a novel parameter for indirect assessment of sufficient spinal cord decompression beyond the levels of surgical exposure.

Indexed as

Intraoperative imagingIntraoperative ultrasoundNon-invasiveSpinal cord compressionSpine surgery

Identifiers

PMID41431682
PMCPMC12718187

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.