ArticleAddiction & health2025
Impact of Opium Addiction on Liver Function and Biliary Tract in Patients with Bile Duct Stones: A Case-Control Study.
Article in Addiction & health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aimed to investigate the impact of opium on liver function and the biliary tract in patients with bile duct stones, comparing outcomes with non-addicted individuals. Methods: This case-control study was conducted in Iran from 2016 to 2017. A total of 86 patients with bile duct stones were divided into two groups: opium-addicted ( Findings: LFTs showed significantly elevated levels of aspartate aminotransferase (AST) (90.67±46.99 vs 55.28±45.53 U/L, Conclusion: The study revealed that opium addiction is associated with significantly elevated levels of liver enzymes (AST and ALT), higher bilirubin levels, and an increased common bile duct diameter in patients with bile duct stones, while the pancreatic duct diameter and ALP levels remained unaffected. These findings highlight the potential impact of opium use on the hepatobiliary system and underscore the importance of further research to understand its long-term effects and improve clinical management.
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