ReviewCureus2025
Evaluation of Root Coverage in Gingival Recessions Treated With Collagen Matrix and Platelet-Rich Fibrin: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of injectable platelet-rich fibrin and microneedling for thin gingival phenotype: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Comparative evaluation of efficacy of xenogeneic pericardial membrane enriched with two different forms of platelet concentrates in the treatment of gingival recession- a randomized clinical trial.Clinical oral investigations · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gingival recession is a common mucogingival defect that results in root exposure, dentinal hypersensitivity, and aesthetic compromise. Various surgical techniques and biomaterials have been employed to achieve predictable root coverage, among which collagen matrices (CM) and platelet-rich fibrin (PRF) have gained clinical prominence. This systematic review aimed to evaluate and compare the efficacy of CM and PRF in achieving root coverage and improving soft-tissue parameters in gingival recession defects. Electronic searches were conducted across PubMed, Web of Science, Scopus, Sciencedirect, EBSCOHost, and Google Scholar databases up to September 2025, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Only randomized controlled trials comparing CM and PRF were included. Six studies involving 210 sites were analyzed qualitatively. Both PRF and CM demonstrated significant improvements in root coverage, gingival thickness, and keratinized tissue width; however, three studies showed superior outcomes with PRF or PRF combined with CM compared to CM alone. Techniques such as the vestibular incision, subperiosteal tunnel access, and pinhole surgical technique, when combined with PRF, provided better soft-tissue outcomes and patient comfort. The overall quality of evidence, evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework, was moderate due to methodological heterogeneity and lack of blinding in outcome assessment. Within the limitations of this review, PRF, either alone or in combination with CM, appears to offer enhanced regenerative outcomes and greater predictability in root coverage procedures compared to CM alone.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.