ArticleCureus2025
A Case Report of Bezoar-Induced Small Bowel Obstruction: A Potential Surgical Complication of Semaglutide.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Bezoars are an uncommon but recognised cause of small bowel obstruction (SBO) and are difficult to differentiate preoperatively from other aetiologies. We report a rare case of acute SBO due to a bezoar in a 65-year-old woman who had been on semaglutide, a Glucagon-like peptide-1 (GLP-1) receptor agonist therapy for weight loss. She presented with a four-day history of abdominal pain, distension, nausea, and vomiting. Imaging confirmed SBO. Following unsuccessful nonoperative management, she underwent diagnostic laparoscopy and laparoscopic resection of a jejunal segment containing a large phytobezoar. We postulated that semaglutide-induced gastroparesis and slow intestinal transit may have contributed to bezoar formation and subsequent bowel obstruction. This case highlights a rare but important surgical adverse effect, particularly in patients receiving GLP-1 receptor agonists who present with bowel obstruction.
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