Evidence map›Paper›PMID 41431478›Full record

ArticleAdvanced materials technologies2024

Intelligent In situ Printing of Multimaterial Bioinks for First-Aid Wound Care Guided by Eye-In-Hand Robot Technology.

Seol-Ha Jeong, Jihyun Kim, Brendan Craig Thibault, Javier Alejandro Lozano Soto, Fatima Tourk, Joshua Steakelum, Diego Azuela, Violeta Carvalho, Guillermo Quiroga-Ocaña, Weida Zhuang and 14 more

Abstract read
In one paragraph

Article in Advanced materials technologies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Immune-Responsive Bioinks Enable Vision-GuidedAdvanced functional materials · 2026
    Article
  2. Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Seol-Ha JeongDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Jihyun KimDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Brendan Craig ThibaultDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Javier Alejandro Lozano SotoDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Fatima TourkDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Joshua SteakelumDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Diego AzuelaDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Violeta CarvalhoDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Guillermo Quiroga-OcañaDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Weida ZhuangDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Mei Li L Cham-PérezDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Lucia L HuangDepartment of Anesthesiology, Perioperative and Pain Medicine, Center for Accelerated Medical Innovation & Center for Nanomedicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Zhuqing LiJoslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Eleftheria-Angeliki ValsamiJoslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Enya WangJoslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Nelson RodriguesMEtRICs, Mechanical Engineering Department, University of Minho, Campus de Azurém, Guimarães 4800-058, Portugal.
Senhorinha F C F TeixeiraALGORITMI/LASI Center, University of Minho, Campus de Azurém, Guimarães 4800-058, Portugal.
Yuhan LeeDepartment of Anesthesiology, Perioperative and Pain Medicine, Center for Accelerated Medical Innovation & Center for Nanomedicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Jungmok SeoSchool of Electrical and Electronic Engineering, Yonsei University, Seoul 03722, Republic of Korea.
Aristidis VevesJoslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Shabir HassanDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.
Georgios TheocharidisJoslin-Beth Israel Deaconess Foot Center and The Rongxiang Xu MD, Center for Regenerative Therapeutics, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Lance FiondellaDepartment of Electrical and Computer Engineering, University of Massachusetts Dartmouth, North Dartmouth, MA 02747, USA.
Su Ryon ShinDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA.

Funding

Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle lossR01AR077132 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI SHIN, SU RYON, TAMAYOL, ALI · 2021 to 2025
$2.6M
Oxygen generating bioinks for 3D printed bone implantsR01AR074234 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI SHIN, SU RYON · 2018 to 2022
$1.9M
Programmable multimaterial bioprinting of 3D vascularized tissue constructsR21EB026824 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI SHIN, SU RYON · 2018 to 2020
$685k
American Heart Association-American Stroke Association 19IPLOI34660079NIAMS NIH HHS R01 AR074234NIAMS NIH HHS R01 AR077132NIBIB NIH HHS R21 EB026824
6 · The paper itself

Abstract

INSIGHT (INtelligent in situ printing Guided by Eye-in-Hand robot Technology), an innovative computer vision-enabled system that combines a depth camera with a 6-degree of freedom robot arm, empowering it to identify arbitrary areas at various angles through real time adjustments and to enable volumetric printing performed by dynamic image recognition based on color and contour differences is presented. Continuous targeting of multiple wounds at different locations is achieved. The optimized pneumatic valve synchronized with the INSIGHT can print multiple inks with diverse rheological properties to fabricate scaffolds and bandages with the capacity to treat various types of wounds. The design of dual printed modes, such as extrusion and spray, can significantly decrease printing time for large-scale wounds on an ex vivo porcine model. INSIGHT demonstrates its ability to treat diabetic wounds, using a microgel-based ink possessing an inherent porous microstructure to facilitate cell infiltration. In vivo verification highlights its adaptability to enable customized care for rapid emergency treatment of trauma patients.

Indexed as

in situ bioprintingrobot printingspray printingvisual guidancewound healing

Identifiers

PMID41431478
PMCPMC12718608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.