ArticleYonsei medical journal2026
Management of Genitourinary Syndrome of Menopause in Korean Breast Cancer Survivors by Fractional CO₂ Laser Treatment.
Article in Yonsei medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Vaginal Laser Therapy for Genitourinary Syndrome of Menopause in Breast Cancer Survivors: A Modality-Specific Systematic Review of Efficacy, Durability, and Safety.Journal of clinical medicine · 2026Review
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Authors and funding
5 authors.
Funding
Abstract
purposeMany breast cancer patients experience genitourinary syndrome of menopause (GSM) symptoms. Concerns about systemic absorption limit the use of local estrogen therapy, and clinicians are often hesitant to prescribe it to breast cancer survivors. Therefore, other treatment options are essential. The aim of this study was to examine the safety and effectiveness of fractional CO₂ laser treatment in breast cancer survivors experiencing GSM. MATERIALS AND
methodsEach woman received three fractional CO₂ treatments at 4-week intervals between sessions: baseline (V1), 4-week follow-up (V2), 8-week follow-up (V3), and a final follow-up at 12 weeks (V4). Breast cancer survivors who had one or more symptoms related to GSM qualified for inclusion in this study. Severity of symptoms was assessed with a visual analog scale (VAS) at baseline and every follow-up visit. We also measured GSM objectively using the vaginal health index score (VHIS) at every visit. At V4, patients evaluated their satisfaction with laser therapy using a 5-point Likert scale.
resultsTwenty-four women were included in the study. Almost all symptoms showed improvement based on mean VAS score after treatment. Vaginal dryness and urgency improved after the second treatment. After completion of all treatments, all symptoms except frequency showed improvement. VHIS increased significantly after completion of laser treatment (8.5±3.1 at baseline vs. 16.2±2.9 at V4;
conclusionFractional CO₂ laser treatment appears to be an effective and safe method in breast cancer survivors with GSM.
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