ArticleBrain and behavior2025
Prediction for Respiratory Failure in Ischemic Stroke Patients Admitted to ICU: A Retrospective Analysis Based on MIMIC-IV Database.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Machine learning prediction models for mechanical ventilation requirement in patients with embolic stroke: a retrospective cohort study based on MIMIC-IV.Frontiers in medicine · 2026Article
- Prediction for Respiratory Failure in Ischemic Stroke Patients Admitted to ICU: A Retrospective Analysis Based on MIMIC-IV Database.Brain and behavior · 2025Article
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4 authors.
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Abstract
introductionThere remains a lack of studies evaluating the risk of respiratory failure in intensive care unit (ICU)-admitted ischemic stroke (IS) patients. We aim to develop a nomogram for the prediction of respiratory failure in those patients and the identification of the patients with high risk of respiratory failure, to facilitate early intervention.
methodsThe medical data of IS patients in the Medical Information Mart for Intensive Care (MIMIC)-IV database were extracted. Variables were selected using Cox stepwise regression, and variables with statistical significance were finally included in the nomogram. The marginal structural Cox model (MSCM) was to adjust for baseline and time varying confounding factors. The calibration curve and Receiver operating characteristic curve (ROC) were applied to assess the performance of the model.
resultsExternal validation using IS patient data from the eICU collaborative ersearch database (eICU-CRD). A total of 3462 eligible patients (2424 in the training set and 1038 in the validation set) were included. The following variables were finally included in the model: infarction location, atrial fibrillation, A alkaline phosphatase (ALP), anion gap (AG), lactic dehydrogenase (LDH), and Na
conclusionWe have developed a nomogram model for the prediction of respiratory failure in IS patients admitted to the ICU, validated using external data. The model could perform effective prediction and thus provide more information for clinicians.
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