ArticleJournal of Korean medical science2025
The Impact of Early-Life, Long-Term Exposure to Ambient Particulate Matter on Atopic Dermatitis Remission and Sensitization in Infants.
Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundStudies that examine a link between long-term exposure to ambient particulate matter (PM) and atopic dermatitis (AD) in children are lacking. This longitudinal study aimed to investigate the effect of long-term exposure to PM on AD in infants.
methodsWe enrolled 150 infants aged 0-1 years with AD and followed them until age 3 in Seoul, Korea. We assessed long-term exposures to ambient particulate matter with an aerodiameter < 10 µm (PM₁₀) from birth to age 3 using a fusion model based on each individual's home address. Effects of long-term exposure to PM₁₀ on AD persistence and sensitization to aeroallergens were evaluated using Cox proportional hazard regression models after adjusting for potential confounders.
resultsOf the 150 infants, 54 (36.0%) showed remission of AD by age 3. Overall, long-term exposure to PM₁₀ was not significantly associated with AD persistence at age 3 (hazard ratio [HR], 1.04; 95% confidence interval [CI], 0.97-1.12;
conclusionAn early-life long-term exposure to ambient PM₁₀ in infants with AD may decrease the remission and increase the sensitization to pollen at age 3.
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