Evidence map›Paper›PMID 41430594›Full record

ArticleBMC musculoskeletal disorders2025

The fate of bone marrow edema after core decompression and bone marrow aspiration concentrate grafting for the hip.

Weiping Su, Boyan Ma, Wenjie Leng, Yixiao Pan, Wenxiu Zhang, Song Wu, Zhi Peng

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Weiping SuDepartment of Orthopedics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China.
Boyan MaDepartment of Orthopedics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China.
Wenjie LengDepartment of Radiology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China.
Yixiao PanDepartment of Orthopedics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China.
Wenxiu ZhangDepartment of Orthopedics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China. 281161743@qq.com.
Song WuDepartment of Orthopedics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China. 600240@csu.edu.cn.
Zhi PengDepartment of Orthopedics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, 410013, China. 13054190137@163.com.

Funding

National Natural Science Foundation of China 82302765Natural Science Foundation of Hunan Province 2022JJ40753The "co-PI" project from The Third Xiangya hospital of Central South University 202421
6 · The paper itself

Abstract

backgroundBone marrow edema (BME) of the femoral head is a prevalent condition that can cause hip pain and is observed in patients as a standalone finding or in conjunction with degenerative or inflammatory conditions. There has been a lack of extensive study on the effectiveness of combining surgery with biological treatment for BME. The objective of this study was to evaluate the efficiency of core decompression (CD) with bone marrow aspirate concentrate (BMAC) augmentation in alleviating pain and enhancing the quality of life in patients with BME in the hip. MATERIALS AND

methodsWe conducted a retrospective analysis of patients who underwent treatment for BME of the hip using CD combined with BMAC between June 2021 and July 2023. Inclusion criteria consisted of patients diagnosed with BME in the hip (presence of BME on T2-weighted MRI in the femoral head or neck with pain corresponding to the same compartment as the BME). The patients' demographic information, presence of other medical conditions, body mass index (BMI), etiology, and assessments using the visual analog scale (VAS) and Harris hip score (HHS) were recorded. Pre- and postoperative radiographic imaging (XR) and magnetic resonance imaging (MRI) were analyzed.

resultsThis study included 28 patients (40 femoral heads) who underwent CD with BMAC grafting at our institution. Among these patients, 9 had normal or non-diagnostic radiographs, 11 were at ARCO stage Ⅰ, and 8 were at ARCO stage Ⅱ. The mean age at the time of operation was 45.21 years (SD 13.17, range 21-75), and the mean BMI was 24.61 (SD 3.75, range 16.6-32.05). The area of BME showed a significant decrease from 954.21 ± 224.68 mm

conclusionTreatment of BME of the hip using CD combined with BMAC is effective and provides short-term pain relief for BME.

Indexed as

Bone Marrow DiseasesBone Marrow TransplantationDecompression, SurgicalEdemaFemur HeadAdultAgedFemaleHip JointHumansMagnetic Resonance ImagingMaleMiddle AgedPain MeasurementQuality of LifeRetrospective StudiesBone marrow aspiration concentrateBone marrow edema syndromesCore decompression

Identifiers

PMID41430594
PMCPMC12837025

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.