ArticleMammalian genome : official journal of the International Mammalian Genome Society2025
Genomic structure and selection history across Angus populations worldwide: insights from ROH, selection mapping, and functional analyses.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Systematic Approach for Compound Angus Populations Revealing Positional Candidate Genes and Improving Prediction Accuracy in Carcass Traits.Animals : an open access journal from MDPI · 2026Article
- Genome-wide association study of mature cow size traits in American Angus cattle.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- The Genomic Landscape of Cattle: Domestication, Dispersal, and Adaptive Evolution.Animals : an open access journal from MDPI · 2026Review
- A comparative study of runs of homozygosity islands common among 12 Australian beef cattle breeds.Journal of animal science · 2026Article
- Disentangling mature cow weight and body condition score: a comparative single-step GWAS of phenotypic pre-adjustment vs. recursive modeling.Journal of animal science · 2026Article
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Authors and funding
11 authors.
Funding
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Abstract
Angus cattle, originally from Scotland, have been selectively bred for over 400 years, making them one of the most prominent beef breeds globally. Known for their adaptability, natural polled traits, and high-quality beef, Angus cattle have been intensively selected for growth, body size, and feed efficiency. This study investigates the genetic diversity, selection history, and key genomic regions across five Angus populations from the USA, Canada, Australia, Brazil, and Red Angus of America. Genomic data from 71,283 animals born between 1961 and 2024 were analyzed using Principal Component Analysis (PCA), phylogenetic tree construction, and Runs of Homozygosity (ROH), with the Generation Proxy Selection Mapping (GPSM) approach used to assess selection history. Functional annotation identified candidate genes and pathways related to selection. Our analysis revealed both similarities and differences across populations. The PCA and FST metrics showed minimal differentiation between the American, Canadian, Australian, and Brazilian populations, with greater differentiation observed in the Red Angus population. The ROH analysis revealed that the Brazilian population had the highest number of ROHs. The ROH islands identified on BTA8 and BTA13 in the American and Australian populations were linked to traits like body weight, marbling, and tenderness. The GPSM identified significant markers associated with body weight and growth in all populations, reflecting ongoing selection pressures. This study highlights the potential of genomics to improve our understanding of Angus cattle's genetic architecture and selection history. It underscores the feasibility of integrating global populations for more accurate genomic evaluations, enhancing genetic predictions, and supporting sustainable beef production worldwide.
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