Evidence map›Paper›PMID 41430475›Full record

ArticleACS synthetic biology2026

Genetically Encoded SpyTag Enables Modular AAV Retargeting via SpyCatcher-Fused Ligands for Targeted Gene Delivery.

Anja Armbruster, Maximilian Hörner, Hanna J Wagner, Claudia Fink-Straube, Wilfried Weber

Abstract read
In one paragraph

Article in ACS synthetic biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Receptor-guided AAV Tropism Engineering via MATCH.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anja ArmbrusterINM - Leibniz Institute for New Materials, Saarbrücken 66123, Germany.
Maximilian HörnerSignalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg i. Br. 79104, Germany.
Hanna J WagnerSignalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg i. Br. 79104, Germany.
Claudia Fink-StraubeINM - Leibniz Institute for New Materials, Saarbrücken 66123, Germany.
Wilfried WeberINM - Leibniz Institute for New Materials, Saarbrücken 66123, Germany.ORCID 0000-0003-4340-4446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recombinant adeno-associated viral (rAAV) vectors are a leading platform for

Indexed as

DependovirusGene Transfer TechniquesPeptidesAnkyrin RepeatCapsidCapsid ProteinsCell Line, TumorEpithelial Cell Adhesion MoleculeErb-b2 Receptor Tyrosine KinasesErbB ReceptorsGenetic TherapyGenetic VectorsHEK293 CellsHumansLigandsCapsid ProteinsEpithelial Cell Adhesion MoleculeERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesErbB ReceptorsLigandsPeptidesAAV capsid engineeringAAV retargetingDARPinsmodular gene delivery, SpyTag/SpyCatchersuicide gene therapy

Identifiers

PMID41430475
PMCPMC12814547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.