Evidence map›Paper›PMID 41430446›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Surgical management outcomes of osteoradionecrosis of the temporal bone: two-centres experience.

Paraskevi Karamitsou, Thomas Parzefall, Panagiotis A Dimitriadis, James Quinn, Neil Donnelly, Patrick Axon, James Tysome, Daniele Borsetto, Ananth Vijendren

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Paraskevi KaramitsouLister Hospital, East and North Hertfordshire Teaching NHS Trust, Stevenage, UK. vivikara28@yahoo.gr.ORCID http://orcid.org/0000-0003-1535-3354
Thomas ParzefallAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Panagiotis A DimitriadisLister Hospital, East and North Hertfordshire Teaching NHS Trust, Stevenage, UK.
James QuinnLister Hospital, East and North Hertfordshire Teaching NHS Trust, Stevenage, UK.
Neil DonnellyAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Patrick AxonAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
James TysomeAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Daniele BorsettoAddenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Ananth VijendrenLister Hospital, East and North Hertfordshire Teaching NHS Trust, Stevenage, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTemporal bone osteoradionecrosis (ORN) is a severe complication that can occur when the temporal bone lies within the field of radiation therapy (RT), mainly for head and neck cancer. Currently, there is no universally accepted treatment approach, but both conservative and surgical management options have been proposed. We present the outcomes of surgically treated cases and propose our surgical strategy for complete management.

methodsA retrospective study was conducted to identify temporal bone ORN cases that were primarily treated surgically at two centres between 2005 and January 2025. We recorded and analysed patients' demographics, the anatomic site of the primary tumors and assessed hearing and other postoperative outcomes.

resultsFourteen cases of ORN of the temporal bone have been identified. Management for these cases varied: six were treated with canaloplasty, two had mastoidectomy with reconstruction, three had lateral temporal bone resection with blind sac closure, three were treated with petrosectomy and blind sac closure. The mean age at diagnosis was 63 years, and half of the cases involved males. The most common site of the primary tumor that received RT was the nasopharynx.

conclusionSurgery is an effective management option for recalcitrant temporal bone ORN. The surgical strategy for temporal bone ORN is guided by disease extent and hearing status. As there are no standardised recommendations for its management, future research is necessary.

Indexed as

Head and Neck NeoplasmsOsteoradionecrosisTemporal BoneAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeCanaloplastyLateral temporal bone resection with blind sac closureOsteoradionecrosisPetrosectomy with blind sac closureRadiation therapyTemporal bone

Identifiers

PMID41430446

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.