Evidence map›Paper›PMID 41430444›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Vestibular implant stimulation can improve self-motion perception.

B L Vermorken, S C J Van Boxel, B Volpe, A Pérez Fornos, N Guinand, E M J Devocht, R van de Berg

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Vestibular implant stimulation can improve self-motion perception.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

B L VermorkenDepartment of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands. bernd.vermorken@mumc.nl.ORCID http://orcid.org/0000-0003-2406-8141
S C J Van BoxelDepartment of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
B VolpeDepartment of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
A Pérez FornosDivision of Otorhinolaryngology Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland.
N GuinandDepartment of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
E M J DevochtDepartment of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.
R van de BergDepartment of Otorhinolaryngology and Head and Neck Surgery, Division of Balance Disorders, Mental Health and Neuroscience Research Institute (MHeNs), Maastricht University, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with bilateral vestibulopathy (BV) typically suffer from a range of symptoms like oscillopsia, unsteadiness and impaired spatial orientation. This orientation is related to the perception of self-motion. Elevated perceptual self-motion thresholds were previously reported in BV patients. This proof-of-concept study evaluated the effect of multi-canal vestibular implant stimulation on perceptual self-motion thresholds.

methodsNine BV patients were implanted with an investigational intralabyrinthine multi-canal vestibulo-cochlear implant (VCI). Eight self-motion perception test sessions were performed, in order to compare three stimulation conditions: VI OFF, VI ON with symmetric modulation and VI ON with asymmetric modulation. A hydraulic platform was used to rotate the patient to measure the perceptual self-motion thresholds for yaw rotations. Rotations towards the implanted side were considered as excitatory stimulations, while rotations away from the implanted side were considered inhibitory stimulations.

resultsA significant improvement in perceptual self-motion thresholds was found during VI stimulation compared to no VI stimulation, when excitatory yaw rotations were applied. This improvement was present during both VI ON symmetric and asymmetric modulation. In contrast, no significant improvement in perceptual self-motion threshold was measured during inhibitory yaw rotations. However, a trend towards improved perceptual thresholds in inhibitory yaw rotations was observed with symmetric modulation. DISCUSSION: The vestibular implant offers potential in improving direction specific self-motion perception for yaw rotations in patients with BV. Consistent with previous findings in vestibular implant research, such as improvements in VOR gain, the effects of excitatory stimulation appear to be more pronounced than those of inhibitory stimulation.

Indexed as

Bilateral VestibulopathyCochlear ImplantsMotion PerceptionAdultAgedFemaleHumansMaleMiddle AgedVestibule, LabyrinthPerceptual thresholdSelf-motion perceptionVestibular implantVestibular stimulation

Identifiers

PMID41430444

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.