Evidence map›Paper›PMID 41430409›Full record

ArticleHeart and vessels2026

Loop technique-based artificial chordae reconstruction in mitral regurgitation.

Takayoshi Kato, Shojiro Yamaguchi, Takatomo Watanabe, Takashi Onuma, Daichi Watanabe, Masayuki Sato, Hiroki Ogura, Etsuji Umeda, Osamu Sakai, Kiyoshi Doi

Abstract read
In one paragraph

Article in Heart and vessels, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takayoshi KatoDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan. kato.takayoshi.f9@f.gifu-u.ac.jp.ORCID http://orcid.org/0000-0001-5121-0006
Shojiro YamaguchiDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Takatomo WatanabeDepartment of Cardiology, Gifu University Graduate School of Medicine, Gifu, Japan.
Takashi OnumaDepartment of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.
Daichi WatanabeDepartment of Pharmacy, Gifu University Hospital, Gifu, Japan.
Masayuki SatoDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Hiroki OguraDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Etsuji UmedaDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Osamu SakaiDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Kiyoshi DoiDepartment of Cardiovascular Surgery, Gifu University Hospital, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the clinical utility of a novel mitral valve repair technique, the Referring to the Anterior, Fixing on the Frontal (RAFF) method, which improves anatomical precision and enhances the reproducibility of loop-type artificial chordae ("neochordae") reconstruction. This retrospective study included 67 individuals who underwent isolated, elective mitral valve repair with neochordae between 2019 and 2024. Participants were divided into the RAFF (n = 36) and non-RAFF (n = 31) groups. In the RAFF technique, chordal length is determined by referencing the anterior leaflet chordae from the ipsilateral papillary muscle, with loop sets anchored to the frontal head of the papillary muscle. Leaflet resection was not performed in any case. Baseline demographics and lesion characteristics were similar between groups. The RAFF group demonstrated significantly less residual mitral regurgitation at the conclusion of surgery (p = 0.014). Use of the RAFF method was significantly associated with suppression of postoperative leaflet billowing and a lower recurrence rate of moderate or greater mitral regurgitation during follow-up. Frontal fixation of posterior leaflet neochordae, a defining feature of the technique, resulted in a significant increase in coaptation length without inducing systolic anterior motion or elevating transvalvular gradients. The method also significantly reduced aortic cross-clamp time without compromising hemodynamic performance. The RAFF technique offers a standardized and anatomically guided approach to neochordae reconstruction. It minimizes inter-surgeon variability and anatomical inconsistencies, and promotes durable mitral competence by optimizing leaflet coaptation without incurring adverse events.

Indexed as

Chordae TendineaeMitral ValveMitral Valve AnnuloplastyMitral Valve InsufficiencyAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeArtificial chordae reconstructionLoop techniqueMitral regurgitationMitral valve repairRAFF method

Identifiers

PMID41430409
PMCPMC13076564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.