Evidence map›Paper›PMID 41430386›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Effect of thickened liquids in facilitating full oral nutrition for the preterm infant struggling to achieve full oral feeds at term postmenstrual age.

Irena K Wilson, Gregory P Jansen, Alicia Hofelich Mohr, Michael Georgieff, Sara Ramel, Kelly Dietz, Holly Shifsky, Katlyn E McGrattan

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irena K WilsonDepartment of Speech-Language-Hearing Sciences, University of Minnesota, Minneapolis, MN, USA.
Gregory P JansenDepartment of Speech-Language-Hearing Sciences, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0009-0005-9471-4577
Alicia Hofelich MohrDepartment of Speech-Language-Hearing Sciences, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-7644-4105
Michael GeorgieffDepartment of Neonatology, University of Minnesota, Minneapolis, MN, USA.
Sara RamelDepartment of Neonatology, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-8485-418X
Kelly DietzDepartment of Radiology, University of Minnesota, Minneapolis, MN, USA.
Holly ShifskyDepartment of Rehabilitation, Masonic Children's Hospital, Minneapolis, MN, USA.
Katlyn E McGrattanDepartment of Speech-Language-Hearing Sciences, University of Minnesota, Minneapolis, MN, USA. kmcgratt@umn.edu.ORCID http://orcid.org/0000-0002-7853-1624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTest the effect of thickened liquids on preterm infants (25-35 weeks of gestation) who are struggling to achieve full oral feeds. STUDY

designRetrospective case-control study of preterm infants struggling to achieve full oral feeds at term, prompting provision of thickened liquids without aspiration on instrumental assessment, and controls, matched for gestational age and comorbidities, who followed a typical thin liquid feeding progression. Paired t-tests were used to test differences in overall milk transfer (%, milk consumed/prescribed) before and after thickening, with mixed linear regression to test differences between the control and thickened group.

result38 infants (19 thickened) were included. Prior to thickening, infants struggling with feeds had significantly slower rates of improvement in overall transfer than controls (struggling feeders, 1.3%/day; controls, 4.5%/day) (p < .001). Overall transfer increased 13% 48 h after thickening (p = 0.01).

conclusionThickened liquids may be an effective treatment for select preterm infants who are not progressing to full oral feeds at term postmenstrual age, even if aspiration is not observed on instrumental assessment.

Indexed as

Enteral NutritionInfant, PrematureCase-Control StudiesFemaleGestational AgeHumansInfant, NewbornInfant Nutritional Physiological PhenomenaLinear ModelsMaleRetrospective Studies

Identifiers

PMID41430386
PMCPMC13190285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.