Evidence map›Paper›PMID 41430118›Full record

ArticleBMC plant biology2025

Comprehensive GWAS and transcriptome analysis discovered new candidate genes for powdery mildew response in pea (Pisum sativum L.).

Xiaojuan Zhong, Mei Yang, Xin Li, Shuangyu Yang, Yuanfang Fan, Xianshu Wang, Chao Xiang

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Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiaojuan ZhongCrop Research Institute of Sichuan Academy of Agricultural Sciences/Environment-friendly Crop Germplasm Innovation and Genetic Improvement Key Laboratory of Sichuan Province, Chengdu, Sichuan, 610066, China.
Mei YangCrop Research Institute of Sichuan Academy of Agricultural Sciences/Environment-friendly Crop Germplasm Innovation and Genetic Improvement Key Laboratory of Sichuan Province, Chengdu, Sichuan, 610066, China.
Xin LiSichuan Seed Station, Sichuan, Chengdu, 610041, China.
Shuangyu YangSichuan Academy of Agricultural Sciences, Chengdu, Sichuan, 610066, China.
Yuanfang FanCrop Research Institute of Sichuan Academy of Agricultural Sciences/Environment-friendly Crop Germplasm Innovation and Genetic Improvement Key Laboratory of Sichuan Province, Chengdu, Sichuan, 610066, China.
Xianshu WangCrop Research Institute of Sichuan Academy of Agricultural Sciences/Environment-friendly Crop Germplasm Innovation and Genetic Improvement Key Laboratory of Sichuan Province, Chengdu, Sichuan, 610066, China.
Chao XiangCrop Research Institute of Sichuan Academy of Agricultural Sciences/Environment-friendly Crop Germplasm Innovation and Genetic Improvement Key Laboratory of Sichuan Province, Chengdu, Sichuan, 610066, China. xc2011cib@163.com.

Funding

Natural Science Foundation of Sichuan Province 2025ZNSFSC0153the 1+9 open competition project of Sichuan Academy of Agricultural Sciences to select the best candidates 1+9 KJGG001the Accurate Identification Project of Crop Germplasm from Sichuan Provincial Finance Department 2025(1+3)ZYGGthe China Agriculture Research System of MOF and MARA-Food Legumes CARS-08the high-level talent introduction project of Sichuan Academy of Agricultural Sciences NKYRCZX2024005
6 · The paper itself

Abstract

backgroundPea powdery mildew is a major disease that causes substantial yield losses and reduces crop quality. Identifying new resistance genes is essential for developing cultivars with durable resistance and high productivity.

resultsIn this study, we applied two complementary approaches, genome-wide association study (GWAS) and transcriptomics, to identify genetic loci and candidate genes involved in the pea response to powdery mildew. For GWAS, infection type (IT) and disease severity (DS) were evaluated in 376 genetically diverse pea accessions grown across four environments. Ten significant single nucleotide polymorphism (SNP) loci were detected for IT in three environments, and eleven loci were detected for DS in two environments; in total, 70 genes were located near these peak SNPs. Transcriptome analysis of one susceptible accession and five resistant accessions was carried out at four infection time points. By integrating GWAS with weighted gene co-expression network analysis (WGCNA) and series test of cluster analysis, we identified eight candidate genes likely contributing to powdery mildew resistance.

conclusionsThese results provide new SNP loci and candidate genes for studying the resistance mechanism of pea powdery mildew and for breeding resistant cultivars.

Indexed as

AscomycotaDisease ResistanceGenes, PlantPisum sativumPlant DiseasesGene Expression ProfilingGenome-Wide Association StudyPolymorphism, Single NucleotideTranscriptomeGenome-wide association study (GWAS)PeaPowdery mildewTranscriptomeWGCNA

Identifiers

PMID41430118
PMCPMC12838418

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