Evidence map›Paper›PMID 41430066›Full record

Observational studyScientific reports2025

Sit to stand and timed up and go in idiopathic inflammatory myopathies.

Tanya Chandra, Raisa L Silva, Shiri Keret, Runjia Li, G K Balasubramani, Ramsha Riaz, Akanksha Sharma, Jesse Wilkerson, Dana P Ascherman, Chester V Oddis and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tanya ChandraDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA. Chandrat3@upmc.edu.
Raisa L SilvaInternal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Shiri KeretFaculty of Medicine, Technion, Haifa, Israel.
Runjia LiDepartment of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
G K BalasubramaniDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Ramsha RiazGeisinger Medical Center, Danville, PA, USA.
Akanksha SharmaUPMC Mercy Hospital, Pittsburgh, PA, USA.
Jesse WilkersonDLH, LLC, Bethesda, MD, USA.
Dana P AschermanDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Chester V OddisDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Siamak Moghadam-KiaDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Rohit AggarwalDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Myositis Patient Centered Tele-Research (My PACER)R01AR071659 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AGGARWAL, ROHIT · 2018 to 2020
$615k
NCATS NIH HHS UL1 TR001857NIAMS NIH HHS R01 AR071659NIH HHS UL1-TR-001857NIH/NIAMS 1R01AR071659
6 · The paper itself

Abstract

Idiopathic inflammatory myopathies can significantly impair physical function, of which Sit to Stand (STS) and Timed Up and Go (TUG) are quick, operator independent measures. We aimed to evaluate psychometric properties of STS and TUG compared to established core set measures of disease activity; and assess feasibility of patients self-performing these tests remotely. Data from a 6-month prospective observational study (Myositis Patient Centered Tele-Research Study -My PACER) was analyzed. Patient-reported and functional assessments were collected monthly over 6 months. A total of 120 patients (75% female, 81% White, mean age 55.5 ± 13.4 years,52% Dermatomyositis, 39% Polymyositis, 9% Necrotizing Myopathy) participated. There was strong test-retest reliability between baseline and month one for STS (r = 0.80) and TUG (r = 0.87); p < 0.01. At baseline, STS and TUG showed a very strong correlation with each other (r = - 0.75) and with most CSMs. Strong correlations were seen with Muscle Disease Activity and a validated Patient Reported Outcome measure of physical function, PROMIS-PF 20. At 6 months, STS and TUG were significantly better among patients who improved according to Total Improvement Score. STS and TUG showed good reliability, even when self-performed remotely using video instructions, with excellent construct validity and responsiveness.

Indexed as

MyositisAdultAgedFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresProspective StudiesPsychometricsReproducibility of Results

Identifiers

PMID41430066
PMCPMC12722296

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.