Evidence map›Paper›PMID 41430028›Full record

ArticleMolecular imaging and biology2026

Lixin Ding, Feng Wang, Yongxiang Pan, Wenting Liu, Liansheng Cheng, Fei Tuo, Kuke Ding, Hua Zhu, Zhi Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lixin DingNational Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing, 100088, China.
Feng WangNMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Yongxiang PanNMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Wenting LiuHefei HankeMab Biotechnology Limited, Hefei, 230088, Anhui, China.
Liansheng ChengHefei HankeMab Biotechnology Limited, Hefei, 230088, Anhui, China.
Fei TuoNational Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing, 100088, China.
Kuke DingNational Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing, 100088, China. dingkk@chinacdc.cn.
Hua ZhuNMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing, 100142, China. zhuhuananjing@163.com.
Zhi YangNMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing, 100142, China. pekyz@163.com.

Funding

Capital's Funds for Health Improvement and Research 2024-2G-30119Major Research Plan of NSFC project 92359203National Natural Science Foundation of China projects 82171973National Natural Science Foundation of China projects 82171980Science Foundation of Peking University Cancer Hospital JC202308Science Foundation of Peking University Cancer Hospital ZY202504Youth Talent Support Program A002863
6 · The paper itself

Abstract

purposeLymphocyte-activation gene 3 (LAG-3), a next-generation immune checkpoint, has emerged as a promising therapeutic target, but noninvasive tools for evaluating LAG-3 expression remain limited. Herein, we explored an antibody-dependent molecular imaging strategy for noninvasive detection based on a LAG-3-specific antibody, HuL13. PROCEDURES: The anti-LAG-3 antibody HuL13 was radiolabeled with

resultsThe

conclusions

Indexed as

Antigens, CDIodine RadioisotopesPositron Emission Tomography Computed TomographyA549 CellsAnimalsHumansLymphocyte Activation Gene 3 ProteinMiceMice, Inbred BALB CMice, NudeTissue DistributionAntigens, CDIodine-124Iodine RadioisotopesLymphocyte Activation Gene 3 ProteinImmune checkpointImmunoPETIodine-124LAG-3Preclinical evaluation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.