Evidence map›Paper›PMID 41429978›Full record

ArticleInternational journal of obesity (2005)2026

Infant social withdrawal and rapid infant weight gain.

Sarah Sander, Anne Christine Stuart, Maria Stougaard, Thorkild I A Sørensen, Julie Elisabeth Warberg Mohr, Mette Skovgaard Væver

Abstract read
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Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sarah SanderCentre of Excellence in Early Intervention and Family Studies, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1917-0304
Anne Christine StuartCentre of Excellence in Early Intervention and Family Studies, Department of Psychology, University of Copenhagen, Copenhagen, Denmark. ach@psy.ku.dk.ORCID 0000-0003-3829-9995
Maria StougaardSteno Diabetes Center Copenhagen, Herlev, Denmark.
Thorkild I A SørensenDepartment of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-4821-430X
Julie Elisabeth Warberg MohrCentre of Excellence in Early Intervention and Family Studies, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0545-4584
Mette Skovgaard VæverCentre of Excellence in Early Intervention and Family Studies, Department of Psychology, University of Copenhagen, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRapid infant weight gain (RIWG) and infant social withdrawal are important early markers of risk of subsequent overweight/obesity and mental health problems, respectively. While overweight and mental health problems are linked later in life, it remains unclear if this association is present already in infancy.

objectiveWe examine if infant social withdrawal is associated with subsequent RIWG independently of an array of known risk factors (gestational age, birth weight, sex, parity, breastfeeding, maternal postpartum depressive symptoms, maternal smoking during pregnancy, maternal age at birth and pre-pregnancy BMI, family educational level, and employment status).

methodsIn a cohort of 12,468 children born 2015-19 in Copenhagen, we analyzed the association between infant social withdrawal around age 3 months, measured with the Alarm Distress Baby Scale (ADBB)-a validated screening tool, and subsequent RIWG. We retrieved information on social withdrawal and weight during infancy from health visitors' records and linked these to register data. Multivariate logistic regression was used to estimate adjusted odds ratios (aOR) and 95% confidence intervals (CI) for RIWG, adjusting for the known risk factors outlined above.

resultsChildren showing signs of social withdrawal had 1.19 higher odds of RIWG compared to children showing no signs of social withdrawal (aOR 1.19; 95% CI: 1.03, 1.37, p = 0.017). RIWG was also more likely among boys, firstborns, children born small-for-gestational age, and those with mothers who smoked during pregnancy or had higher pre-pregnancy BMI. In contrast, higher birth weight and breastfeeding >4 months were protective factors. No associations were found with maternal postpartum depression, low education, parental labor market status, or maternal age.

conclusionsWe found an association between infant social withdrawal and subsequent rapid infant weight gain independently of an array of known risk factors, which may expand our understanding of the developmental origins of excess weight gain and its association with early childhood mental health.

Indexed as

Social IsolationWeight GainAdultBody Mass IndexCohort StudiesDenmarkFemaleHumansInfantInfant, NewbornMalePediatric ObesityPregnancyRisk Factors

Identifiers

PMID41429978
PMCPMC12965871

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.