Evidence map›Paper›PMID 41429898›Full record

ArticleNature communications2025

Constructing the human brain metabolic connectome with MR spectroscopic imaging reveals cerebral biochemical organization.

Federico Lucchetti, Edgar Céléreau, Pascal Steullet, Yasser Alemán-Gómez, Patric Hagmann, Antoine Klauser, Paul Klauser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federico LucchettiCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-9778-8460
Edgar CéléreauCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0009-0006-6817-4092
Pascal SteulletCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-7025-2903
Yasser Alemán-GómezConnectomics Lab, Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-6067-8639
Patric HagmannConnectomics Lab, Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Antoine KlauserSwiss Innovation Hub, Siemens Healthineers International AG, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-3019-9914
Paul KlauserCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. paul.klauser@unil.ch.ORCID http://orcid.org/0000-0003-0284-4947

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 215728
6 · The paper itself

Abstract

Network science has mapped brain structural and functional organization, yet capturing metabolic contrast remains a major gap in connectomics. Using fast, high-resolution 3D whole-brain proton magnetic resonance spectroscopic imaging (

Indexed as

BrainConnectomeAdultFemaleGray MatterHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedProton Magnetic Resonance SpectroscopyYoung Adult

Identifiers

PMID41429898
PMCPMC12727723

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.