ReviewBone research2025
Bibliometric and LDA analysis of extracellular vesicles in osteoarthritis.
Review in Bone research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bibliometric and LDA analysis of the correlation between childhood obesity and precocious puberty (2005-2025).Frontiers in pediatrics · 2026Pooled it
- From pathogenic to reparative: Context-Dependent function of extracellular vesicles in osteoarthritis.Bioactive materials · 2027Review
- Charting the artificial intelligence revolution in orthodontics : A bibliometric analysis of key players, collaborations, and research directions.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026Review
- The Infrapatellar Fat Pad in Osteoarthritis: From Pathophysiology to a Novel Therapeutic Target.International journal of molecular sciences · 2026Review
- Mammalian cell-derived extracellular vesicles remodel the immune-repair microenvironment in osteoarthritis: from pathological signal transmission to regenerative therapy.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Osteoarthritis (OA) is a common degenerative joint disease with complex risk factors, and its underlying mechanism remains unclear. The disease has a subtle onset and mild early symptoms, and its progression is irreversible. Current treatments do not offer a complete cure. Therefore, developing new therapies, early prevention strategies, and reliable biomarkers is essential to reduce the disease burden and improve the quality of life for OA patients. Extracellular vesicles, with their natural biocompatibility and low immunogenicity, have shown great potential in drug delivery and acellular therapies. To provide a complete understanding of the current research and future prospects of extracellular vesicles in OA, this study used bibliometric analysis and Latent Dirichlet Allocation (LDA) methods to systematically evaluate international collaborations, research hotspots, and emerging trends in the field. Our aim is to offer a scientific basis and reference for innovative OA treatment strategies and the clinical application of extracellular vesicles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.