Evidence map›Paper›PMID 41429599›Full record

ArticlePediatric obesity2026

Starting Age for Screening Metabolic Dysfunction-Associated Steatotic Liver Disease in Children Using Controlled Attenuation Parameter on Transient Elastography.

Li-Wen Lee, Jrhau Lung, Ju-Bei Yen, Chao-Yu Chen, Yu-San Liao

Abstract read
In one paragraph

Article in Pediatric obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Li-Wen LeeDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Jrhau LungSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ju-Bei YenDepartment of Pediatrics, Chang Gung Memorial Hospital, Chiayi, Taiwan.
Chao-Yu ChenDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chiayi, Taiwan.ORCID https://orcid.org/0000-0001-6111-2602
Yu-San LiaoSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Funding

Chang Gung Medical Foundation CMRPG6P0241Ministry of Science and Technology, Taiwan MOST 109-2314-B-182A-100
6 · The paper itself

Abstract

backgroundRising sedentary behaviour and consumption of sugar-sweetened beverages and ultra-processed foods have increased the risk and earlier onset of obesity in children.

objectivesTo define controlled attenuation parameter (CAP) cut-off values in healthy children, assess the prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) in children with overweight and obesity, and establish an appropriate starting age for MASLD screening in our population.

methodsHealthy primary school children were recruited. Hepatic steatosis was assessed using CAP, and body composition data were collected during two periods: August 2020-March 2021 and February 2023-May 2024.

resultsOf 1653 participants (mean age 9.5 ± 1.7 years), 976 children with normal weight were used to establish reference intervals. Hepatic steatosis was defined as a CAP above 247 dB/m (97.5th percentile). The prevalences of MASLD in children with overweight and obesity were 0% and 16%, respectively, in school grade 1, which increased to 19% and 75% in school grade 6 (p < 0.001).

conclusionsScreening for hepatic steatosis associated with obesity should begin as early as school grade 1, while screening for children with overweight may be more appropriate by school grade 6. These findings emphasise the need for age- and weight-specific screening strategies for children with overweight and obesity.

Indexed as

Elasticity Imaging TechniquesFatty LiverMass ScreeningNon-alcoholic Fatty Liver DiseasePediatric ObesityAge FactorsChildFemaleHumansMalePrevalencefatty liver diseasepaediatric obesityvibration controlled transient elastography

Identifiers

PMID41429599
PMCPMC12722110

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.