Evidence map›Paper›PMID 41429292›Full record

ArticleJournal of substance use and addiction treatment2025

Cigarette use and smoking cessation goals among pregnant women with opioid use disorder.

Elizabeth E Krans, Daniel Lewis, Antoine Douaihy, Michelle R Lofwall, Frankie Kropp, Peter R Martin, Reesha S Sanghani, Jesse N Cottrell, T John Winhusen

Registry-linked trialAbstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03918850 (Medication Treatment for Opioid Use Disorder in Expectant Mothers), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03918850 phase3completednot on this map

Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs): a Pragmatic Randomized Trial Comparing Extended-release and Daily Buprenorphine Formulations

TypeinterventionalSponsorT. John Winhusen, PhDRan2020 to 2025Enrolled140ConditionsOpioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance AbuseArmsBuprenorphine Injection, Buprenorphine Sublingual Product
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elizabeth E KransDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, USA; Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA. Electronic address: kransee@upmc.edu.
Daniel LewisDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH, 45229, USA; Center for Addiction Research, University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, 45267, USA.
Antoine DouaihyUniversity of Pittsburgh School of Medicine, Department of Psychiatry, Western Psychiatric Hospital, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Michelle R LofwallDepartments of Behavioral Science and Psychiatry, Center on Drug and Alcohol Research University of Kentucky College of Medicine, Lexington, KY, 40508, USA.
Frankie KroppDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH, 45229, USA; Center for Addiction Research, University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, 45267, USA.
Peter R MartinDepartments of Psychiatry and Behavioral Sciences and PharmacologyVanderbilt University School of Medicine, Nashville, TN, 37212, USA.
Reesha S SanghaniDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Vanderbilt University School of Medicine, Nashville, TN, 37212, USA.
Jesse N CottrellDepartment of Obstetrics and Gynecology, Marshall University, Joan C. Edwards School of Medicine, 1600 Medical Center Drive, Huntington, WV, 25701, USA.
T John WinhusenDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH, 45229, USA; Center for Addiction Research, University of Cincinnati College of Medicine, 3230 Eden Ave, Cincinnati, OH, 45267, USA.

Funding

The Ohio Valley Node of the Clinical Trials Network (CTN-0153)UG1DA013732 · NIDA · UNIVERSITY OF CINCINNATI · PI T John WINHUSEN · 2015 to 2026
$42.5M
NIDA NIH HHS UG1 DA013732
6 · The paper itself

Abstract

introductionCigarette smoking rates among pregnant women with opioid use disorder (OUD), are significantly higher than those found in the general population.

methodsWe conducted a secondary analysis of baseline data from a multisite, randomized clinical trial comparing two different buprenorphine formulations on outcomes during pregnancy. Cigarette use and smoking cessation goals were evaluated with the Fagerström Test for Nicotine Dependence and the Thoughts About Abstinence (TAA) questionnaire respectively. Factors associated with differences in cigarette use and smoking cessation goals were compared.

resultsAmong 156 participants, 85 (54.5 %) reported that they currently smoked cigarettes. Most participants had a desire to quit smoking (TAA score = 6), but they had low expectations of success (TAA score = 4) and a relatively high perceived difficulty (TAA score = 6.5) of quitting during pregnancy. Among participants who smoked, less than half (45.5 %) had a smoking cessation goal. Participants who had a smoking cessation goal were significantly more likely to have a stronger desire to quit and higher expectations of success in quitting than participants who did not have a goal.

conclusionsMany pregnant women with OUD would like to quit or reduce smoking during pregnancy. A combination of pharmacologic and non-pharmacologic interventions to reduce or eliminate cigarette use should be incorporated into obstetric and substance use treatment clinical settings. Smoking cessation interventions should be aligned with patients' goals and preferences.

trial registrationClinical Trials.govhttp://www. CLINICALTRIALS: gov; Identifier: NCT03918850.

Indexed as

CigarettesOpioid use disorderPregnancyTobacco

Identifiers

PMID41429292
PMCPMC13072691

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Registered trials

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