Evidence map›Paper›PMID 41429291›Full record

Trial reportJournal of substance use and addiction treatment2026

An economic analysis of Native CHOICES.

Robert Rosenman, Carolyn Noonan, Richard F MacLehose, Jessica Hanson, Kyra Oziel, Karen Little Wounded, Serea Darnell, Marcia O'Leary, Michelle Sarche, Dedra Buchwald

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of substance use and addiction treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Robert RosenmanSchool of Economic Sciences, Washington State University, Pullman, WA, 99163, USA. Electronic address: yamaka@wsu.edu.
Carolyn NoonanInstitute for Research and Education to Advance Community Health, Elson S. Floyd College of Medicine, Washington State University, 1100 Olive Way, Suite 1200, Seattle, WA, 98101, USA.
Richard F MacLehoseDivision of Epidemiology and Community Health, University of Minnesota, 300 West Bank Office Building, 1300 S. 2(nd) Street, Minneapolis, MN, 55454, USA.
Jessica HansonDepartment of Applied Human Sciences, University of Minnesota Duluth, 1216 Ordean Court, Duluth, MN, 55812, USA.
Kyra OzielInstitute for Research and Education to Advance Community Health, Elson S. Floyd College of Medicine, Washington State University, 1100 Olive Way, Suite 1200, Seattle, WA, 98101, USA.
Karen Little WoundedMissouri Breaks Industries Research Inc., 505 S. Willow Street, P.O. Box 1824, Eagle Butte, SD, 57625, USA.
Serea DarnellMissouri Breaks Industries Research Inc., 505 S. Willow Street, P.O. Box 1824, Eagle Butte, SD, 57625, USA.
Marcia O'LearyMissouri Breaks Industries Research Inc., 505 S. Willow Street, P.O. Box 1824, Eagle Butte, SD, 57625, USA.
Michelle SarcheBuffett Early Childhood Institute at the University of Nebraska, 2111 S. 67(th) Street, Omaha, NE, 68106, USA.
Dedra BuchwaldNeurosciences Institute Department of Neurological Surgery, University of Washington, 908 Jefferson St, Seattle, WA, 98104, USA.

Funding

Transition to RecoveryP60AA026112 · NIAAA · WASHINGTON STATE UNIVERSITY · PI Denise A Dillard, Michael G McDonell · 2018 to 2026
$10.7M
NIAAA NIH HHS P60 AA026112
6 · The paper itself

Abstract

introductionFetal alcohol spectrum disorders (FASDs) are a costly collection of conditions caused by alcohol exposed pregnancies (AEPs). Changing High-Risk Alcohol Use and Increasing Contraception Effectiveness Study (CHOICES) is an evidence-based CDC program for AEP prevention. Native CHOICES is a cultural adaptation of CHOICES shown to be effective for reducing AEP risk in American Indian communities. The current study represents the first economic analysis of Native CHOICES.

methodsUsing pre-pandemic data from a randomized controlled trial of Native CHOICES in a Northern Plains American Indian community, the cost-benefit, cost effectiveness, and quality of adjusted life years (QALY) were assessed for Native CHOICES.

resultsNative CHOICES lowered AEP risk by 18-20 % during the 6 months following program participation, thus lowering FASDs by an estimated 6.84-7.6 %. Economic analysis of Native CHOICES' impact on lowered AEP and FASD risk revealed Native CHOICES' net economic benefit of $308,295 to $376,951 for the 6 months following the program, with cost efficiency ratios for FASDs avoided ranging from $84,887 to $93,709, and $2330 to $2572 per quality adjusted life years gained.

conclusionEconomic analysis results indicate that Native CHOICES is a cost-effective program for AEP and FASD prevention among American Indian participants in the intervention.

Indexed as

Choice BehaviorCost-Benefit AnalysisFetal Alcohol Spectrum DisordersIndians, North AmericanAdultFemaleHumansPregnancyQuality-Adjusted Life YearsAlcohol exposed pregnanciesCost benefitCost efficiencyFetal alcohol spectrum disorders

Identifiers

PMID41429291
PMCPMC12830034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.