Evidence map›Paper›PMID 41428879›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A conserved hub protein required for peptidoglycan remodeling and cell division in

Brent W Simpson, Amanda B McLean, M Stephen Trent

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Control of cell division by anbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brent W SimpsonDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.
Amanda B McLeanDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.ORCID 0000-0003-3153-8017
M Stephen TrentDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602.ORCID 0000-0001-6134-1800

Funding

Function and maintenance of molecules at the surface of Acinetobacter baumanniiF32GM137554 · NIGMS · UNIVERSITY OF GEORGIA · PI SIMPSON, BRENT · 2020 to 2021
$131k
DOD | USA | AFC | CCDC | ARO | Life Sciences Division, Army Research Office (Life Sciences Division ARO) W911NF2010195HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI176776 AI138576 AI50098NIGMS NIH HHS F32 GM137554
6 · The paper itself

Abstract

Gram-negative bacteria build a multilayered cell envelope in which the peptidoglycan layer is sandwiched between an inner membrane of glycerophospholipids and an asymmetric outer membrane composed of glycerophospholipids and lipopolysaccharide (LPS).

Indexed as

Acinetobacter baumanniiBacterial ProteinsCell DivisionCell WallPeptidoglycanAmidohydrolasesEnzyme ActivationSyntenyamidaseAmidohydrolasesBacterial ProteinsPeptidoglycanAcinetobacter baumanniiamidase activatorbeta-lactamasecell wallpeptidoglycan

Identifiers

PMID41428879
PMCPMC12772221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.