Evidence map›Paper›PMID 41428722›Full record

ArticleJBRA assisted reproduction2026

A 3PN zygote can be transferred after PGT-A and embryo ploidy analysis: A case report of a healthy neonate.

Eliana Margarita Retamoso-Paz, Marisol Martínez-Martínez, Luz Sthefany Chavarro-Tello, Clara Inés Esteban-Pérez

Abstract readCase Reports
In one paragraph

Article in JBRA assisted reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eliana Margarita Retamoso-PazDepartment of Gynecology and Obstetrics. Universidad del Sinú EBZ. Cartagena, Colombia.
Marisol Martínez-MartínezFIV Laboratory, Cecolfes. Cartagena, Colombia.
Luz Sthefany Chavarro-TelloDepartment of Gynecology and Obstetrics. Universidad del Sinú EBZ. Cartagena, Colombia.
Clara Inés Esteban-PérezReproductive Genomic. Invitrocell S.A.S. Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a healthy live birth following in vitro fertilization (IVF) resulting from the transfer of a euploid embryo derived from a tri-pronuclear zygote (3PN), along with a review of related literature. The case occurred at a private IVF center. It involves a nulliparous 29-year-old woman with abnormal ovarian reserve and male factor infertility who underwent IVF. Preimplantation genetic testing for aneuploidy and noninvasive prenatal testing with cell-free fetal DNA indicated normal ploidy. This report provides evidence that transferring a euploid embryo from an abnormally fertilized oocyte (tri-pronuclear zygote) can lead to a clinical pregnancy and a healthy live birth.

Indexed as

Embryo TransferPloidiesPreimplantation DiagnosisZygoteAdultFemaleFertilization in VitroHumansInfant, NewbornLive BirthMalePregnancy3PN embryocase reportICSINGSPGT-ASNP

Identifiers

PMID41428722
PMCPMC13055190

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.