ArticleJBRA assisted reproduction2026
Influence of human papillomavirus on semen parameters and male infertility: a single-center study.
Article in JBRA assisted reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Molecular Advances in Male Infertility and Fertility: Importance of Redox Regulation and Oxidative Stress.International journal of molecular sciences · 2026Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo detect the presence of seminal HPV and examine its association with semen quality in men from infertile and fertile couples.
methodsThis single-center case-control study involved 50 men from infertile couples and 10 proven-fertility men as controls. Semen samples collected were analyzed using computer-aided semen analysis and tested for HPV detection and genotyping with real-time PCR.
resultsHPV DNA was detected in the semen of 9 men from infertile couples (18.0%) and 1 proven-fertility control (10.0%). Among infertile couples, HPV positivity was linked to significantly altered semen parameters: increased progressive motility (p=0.0399), higher presence of sperm with excess residual cytoplasm (p=0.05), and a lower percentage of normal acrosomes (p=0.05). Kinematic measurements, including straight-line velocity (VSL, p=0.0235), average path velocity (VAP, p=0.0434), linearity (LIN, p=0.05), wobble (WOB, p=0.05), and beat cross frequency (BCF, p=0.0239), were significantly higher in HPV-positive infertile men. Compared to fertile controls, HPV-positive men from the infertile group showed significantly lower sperm concentration (p=0.0493), total motile sperm count (p=0.0291), and mucus penetration ability (p=0.0088), along with a reduced percentage of morphologically normal sperm (p=0.05). Conversely, they had higher rates of sperm with excess residual cytoplasm (p=0.05), tail deformities (p=0.05), and neck and midpiece deformities (p=0.0499).
conclusionsSeminal HPV is associated with impaired sperm parameters in infertile men. This highlights HPV's role as a potential contributing factor in male infertility, warranting further investigations.
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