Evidence map›Paper›PMID 41428415›Full record

Trial reportInterdisciplinary cardiovascular and thoracic surgery2026

Feasibility and Efficacy of Mobile Three-Dimensional c-Arm Systems for Single-Stage Localization and Resection of Small Pulmonary Nodules: A Pilot Clinical Trial.

Hsin-Yueh Fang, Chuan Cheng, Pin-Li Chou, Yin-Kai Chao

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04974632 (Mobile 3D C-arm CT for Lung Tumor Localization Efficacy Analysis), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04974632 nacompletednot on this map

Mobile 3D C-arm CT for Lung Tumor Localization Efficacy Analysis: a Prospective Clinical Trial

TypeinterventionalSponsorChang Gung Memorial HospitalRan2021 to 2022Enrolled41ConditionsLung Tumor, Thoracoscopic SurgeryArmslocalization
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hsin-Yueh FangDivision of Thoracic Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0001-5382-8133
Chuan ChengDivision of Thoracic Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Pin-Li ChouDivision of Thoracic Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Yin-Kai ChaoDivision of Thoracic Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0001-8649-8783

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHybrid operating rooms (HORs) incorporating robotic C-arm systems facilitate concurrent localization and resection of small pulmonary nodules, albeit with significant cost barriers. Contemporary mobile 3 D C-arm systems may provide superior soft tissue visualization with enhanced economic viability and accessibility. This prospective single-arm clinical pilot trial was designed to assess the technical feasibility, clinical efficacy, and procedural safety of employing mobile 3 D C-arm technology for single-stage localization and excision of small pulmonary nodules.

methodsPatients presenting with small and/or deep-seated lung tumors necessitating preoperative localization were eligible for inclusion. Two distinct mobile 3 D C-arm systems (Cios Spin and Ziehm Vision RFD 3 D) were employed. The primary end-points included the rate of successful tumour localization and the time required to complete the localization procedure. Secondary end-points encompassed perioperative complications and radiation exposure.

resultsThe study cohort included 41 patients with lung tumors measuring a median diameter of 7.30 mm (interquartile range [IQR]: 5.00-9.20 mm) and a median depth of 10.00 mm (IQR: 2.00-18.00 mm). Successful localization was achieved in 40 patients, yielding a success rate of 97.6%. In one case, inadequate lesion visualization using the mobile 3 D C-arm necessitated localization in a hybrid operating room. The mean localization time was 27.17 ± 10.38 min, and the median radiation exposure was 531.04 μGy m2 (IQR: [297.12-870.98] μGy m2). All patients were successfully discharged, with a median postoperative hospital stay of 3 days (IQR: 3-3 days).

conclusionsOur results support the technical feasibility, clinical efficacy, and procedural safety of mobile 3 D C-arm systems for single-stage localization and resection of small pulmonary nodules. CLINICAL TRIAL REGISTRATION NUMBER: ClinicalTrials.gov identifier: NCT04974632.

Indexed as

Imaging, Three-DimensionalLung NeoplasmsMultiple Pulmonary NodulesPneumonectomyRobotic Surgical ProceduresSolitary Pulmonary NoduleAgedEquipment DesignFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsProspective StudiesTreatment Outcome3D C-arm systemslocalizationresectionsmall pulmonary nodules

Identifiers

PMID41428415
PMCPMC12957938

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.