Evidence map›Paper›PMID 41428358›Full record

ArticleThe veterinary quarterly2026

Perfect diagnostic agreement between canine- and feline-specific parvovirus PoC antigen kits in feline panleukopenia.

Mahmoud S Safwat, Manar M Farouk, Ahmad Zaki Anwer, M E Ali, Nehal M Shahen, Dina A Abdelwahed, Rabab T Hassanien, Ahmed F Afify, M H Ali, Samah Eid and 5 more

Abstract read
In one paragraph

Article in The veterinary quarterly, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mahmoud S SafwatDepartment of Internal Medicine and Infectious Diseases (Infectious Diseases), Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Manar M FaroukDepartment of Internal Medicine and Infectious Diseases (Infectious Diseases), Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Ahmad Zaki AnwerDepartment of Internal Medicine and Infectious Diseases (Infectious Diseases), Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
M E AliDepartment of Internal Medicine and Infectious Diseases (Internal Medicine), Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Nehal M ShahenVirology Research Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Dina A AbdelwahedVirology Research Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Rabab T HassanienVirology Research Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Ahmed F AfifyVirology Research Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
M H AliVirology Research Department, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Samah EidDepartment of Bacteriology, Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Othman N O MansourGenome Research Unit (GRU), Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Mary A N SargiousGenome Research Unit (GRU), Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Mohamed I AbdallahGenome Research Unit (GRU), Animal Health Research Institute (AHRI), Agriculture Research Center (ARC), Dokki, Giza, Egypt.
Reham KaramDepartment of Virology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Samah El-Sayed MDepartment of Internal Medicine and Infectious Diseases (Infectious Diseases), Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Timely diagnosis is essential for managing feline panleukopenia (FPL), a devastating disease of cats caused by feline parvovirus (FPV) or canine parvovirus variants (CPV-2a, -2b, -2c). To support swift clinical decisions, point-of-care (PoC) antigen kits offer frontline tools. Given their cost and availability advantages, CPV-specific kits are often used off-label in cats; however, their interchangeability with manufacturer-matched FPV-specific kits remains unverified. This study assessed the diagnostic agreement between paired canine- and feline-specific PoC parvovirus antigen tests from two manufacturers. Fifty cats (30 with acute gastroenteritis, 20 healthy) were tested using all test formats. All cats underwent PCR and sequencing for parvovirus typing. Tests from the same manufacturer showed near-perfect or perfect agreement for result interpretation (Cohen's κ: 0.919 and 1.000). This strong inter-kit concordance also extended to test line intensity (

Indexed as

Antigens, ViralCat DiseasesFeline PanleukopeniaFeline Panleukopenia VirusParvoviridae InfectionsParvovirus, CanineReagent Kits, DiagnosticAnimalsCatsDogsPoint-of-Care SystemsPolymerase Chain ReactionAntigens, ViralReagent Kits, DiagnosticAgreementcanine parvovirusfeline parvovirusoff-labelpartial sequencingPCRpoint-of-Care kitsVP2 gene

Identifiers

PMID41428358
PMCPMC12724100

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.