ArticleCEN case reports2025
Hypokalemic rhabdomyolysis due to concurrent distal renal tubular acidosis and Fanconi syndrome in a pediatric patient with Sjögren syndrome.
Article in CEN case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A 16-year-old Japanese girl presented to the emergency department with a complaint of increased muscle pain in the thighs and difficulty walking. Laboratory examinations revealed elevated levels of creatine phosphokinase, severe hypokalemia (1.4 mmol/L), hyperchloremic metabolic acidosis with a normal anion gap, and a urinary pH of 7.5. The patient was thus diagnosed with hypokalemic rhabdomyolysis due to distal renal tubular acidosis. Furthermore, the patient was diagnosed with Sjögren syndrome based on a high titer of anti-SS-A antibodies, reduced tear production on the Schirmer test, decreased salivary secretion on the Saxon test, and labial salivary gland pathology. Although her muscle symptoms resolved rapidly with fluid and potassium replacement therapy, hypophosphatemia and hypouricemia persisted. The patient was subsequently diagnosed with Fanconi syndrome based on elevated urinary β
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