Evidence map›Paper›PMID 41428221›Full record

ArticleCurrent microbiology2025

Antibacterial Activity, Phytochemical Composition, and Cytotoxicity Evaluation of Select Medicinal Plants from Bangladesh.

Farhana Ahmed, Walter Luyten, Alokesh Kumar Ghosh, Jan Paeshuyse

Abstract read
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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Farhana AhmedDepartment of Biosystems, Division Animal and Human Health Engineering, Kasteelpark Arenberg 30, KU Leuven, 3001, Belgium. farhana.ahmed@kuleuven.be.ORCID http://orcid.org/0000-0001-6193-7970
Walter LuytenDepartment of Biology, Animal Physiology and Neurobiology Section, Zoological Institute, Naamsestraat 59, KU Leuven, 3000, Belgium.
Alokesh Kumar GhoshFisheries and Marine Resource Technology Discipline, Khulna University, Khulna, 9208, Bangladesh.
Jan PaeshuyseDepartment of Biosystems, Division Animal and Human Health Engineering, Kasteelpark Arenberg 30, KU Leuven, 3001, Belgium. jan.paeshuyse@kuleuven.be.

Funding

Prime Minister Fellowship, Bangladesh Date: 09/08/2021Prime Minister Fellowship, Bangladesh Memo No:03.03.2690.094.18.03.21-472
6 · The paper itself

Abstract

Bangladesh's rich plant diversity offers an underexplored source of plant-based antibacterials with the potential to strengthen sustainable aquaculture. This study evaluated the in vitro antibacterial efficacy of 55 Bangladeshi plants against five key fish pathogens, including Aeromonas hydrophila, Pseudomonas fluorescens, Pseudomonas aeruginosa, Flavobacterium columnare, and Streptococcus iniae. The findings revealed numerous plant extracts with potential antibacterial activity against test pathogens. Among pathogens, S. iniae and F. columnare were found to be the most susceptible to the majority of plants. Several plants exhibited promising broad-spectrum antibacterial activity, including Terminalia arjuna, Terminalia bellirica, Mikania micrantha, Peperomia pellucida, Lawsonia inermis, Phyllanthus emblica, Eryngium foetidum, Amaranthus spinosus, and Alstonia scholaris. Novel antibacterial activity was reported for Ipomoea quamoclit, Erythrina serrata, Cressa europaea, and Dillenia indica against all tested pathogens, along with first-time screenings of the majority of plants against F. columnare and S. iniae. Phytochemical analysis revealed diverse bioactive groups in potent active extracts, including flavonoids, terpenoids, phenolics, glycosides, alkaloids, and steroids. While a few potent extracts showed moderate cytotoxicity on the human embryonic kidney (HEK293) cell line, the majority were found to be safe. These findings highlight the significant potential of Bangladeshi flora as a source of novel, eco-friendly therapeutics for sustainable aquaculture disease management. This work provides a critical foundation for the future exploration of these plants, including the isolation of active compounds and subsequent in vivo studies, which could ultimately contribute to reducing reliance on conventional antibiotics.

Indexed as

Anti-Bacterial AgentsBacteriaPhytochemicalsPlant ExtractsPlants, MedicinalAnimalsBangladeshFish DiseasesHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsPhytochemicalsPlant Extracts

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.