Evidence map›Paper›PMID 41428094›Full record

ArticleCurrent microbiology2025

Characterization and Genomic Analysis of the First Phage Infecting Vibrio hyugaensis, vB_VhyS_SJ1.

Suqing Zhang, Wei Wang, Xin Chen, Ziyue Wang, Xiangyun Chen, Zhaobin Zheng, Ni Wang, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong and 4 more

Abstract read
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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Suqing Zhang *MoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Wei Wang *MoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Xin Chen *MoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Ziyue WangMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Xiangyun ChenQingdao Benzo Chemical Co. Ltd, Qingdao, China.
Zhaobin ZhengMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Ni WangMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Yeong Yik SungUMT-OUC Joint Centre for Marine Studies, Qingdao, China.
Wen Jye MokUMT-OUC Joint Centre for Marine Studies, Qingdao, China.
Li Lian WongUMT-OUC Joint Centre for Marine Studies, Qingdao, China.
Min WangMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China.
Hongbing ShaoMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China. hbshao@ouc.edu.cn.
Yundan LiuMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China. liuyundan@ouc.edu.cn.
Yantao LiangMoE Key Laboratory of Evolution & Marine Biodiversity, College of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Frontiers Science Center for Deep Ocean Multispheres and Earth System, Center for Ocean Carbon Neutrality, Ocean University of China, Qingdao, China. liangyantao@ouc.edu.cn.

Funding

Fundamental Research Funds for the Central Universities 201812002Fundamental Research Funds for the Central Universities 202072001Fundamental Research Funds for the Central Universities 202172002Laoshan Laboratory No. LSKJ202203206Natural Science Foundation of China No. 42120104006Natural Science Foundation of China No.42176111Postdoctoral Research Foundation of China 2025M770867
6 · The paper itself

Abstract

Vibrio hyugaensis is an opportunistic pathogen widely distributed in marine environments. Phages are considered an important method for controlling pathogenic bacteria. However, phages infecting V. hyugaensis have not yet been reported. In this study, a novel phage infecting V. hyugaensis, named vB_VhyS_SJ1, was isolated from nearshore surface seawater of Qingdao, China. Transmission electron microscopy showed that it had a siphoviral morphology. vB_VhyS_SJ1 exhibits a latent period of 10 min and a burst size of 52 ± 2 PFU/infected bacterium. It is stable over a temperature range of 4 °C to 65 °C and remains stable within a pH range of 5 to 10. The inhibition ability of the vB_VhyS_SJ1 against the V. hyugaensis was tested in vitro using the vB_VhyS_SJ1 with four multiplicity of infection (MOI) values. All treated groups effectively inhibited the growth compared to the untreated culture of V. hyugaensis within 12 h. The genome of vB_VhyS_SJ1 is double-stranded DNA, with a genome size of 121,361 bp, containing 174 putative open reading frames (ORFs). Four auxiliary metabolic genes (AMGs) were predicted, and a total of 25 tRNA genes were identified. Phylogenetic and genomic network analysis demonstrated that vB_VhyS_SJ1 belongs to the Pogseptimavirus genus of the Demerecviridae family. Additionally, biogeographical distribution analysis found that vB_VhyS_SJ1 is primarily found in temperate, and tropical epipelagic zones with low abundance. Overall, this study provides a characterization of the first phage infecting the opportunistic pathogenic V. hyugaensis.

Indexed as

BacteriophagesGenome, ViralSiphoviridaeVibrioChinaDNA, ViralGenomicsOpen Reading FramesPhylogenySeawaterDNA, Viral

Identifiers

PMID41428094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.