Evidence map›Paper›PMID 41427835›Full record

ArticleMicrobiology spectrum2026

PI3K/Akt/mTOR signaling pathway mediates energy metabolic reprogramming and regulates mitochondrial homeostasis in host cells exposed to

Kangzhi Xu, Shifan Zhu, Jing Ma, Mingyue Zu, Jin Yang, Fan Xu, Linwei Dai, Dandan Liu, Yanhong Wang, Xinjun Zhang and 5 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Trem2 negatively regulates the MTOR-PKCα axis to protect againstFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kangzhi XuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0003-4536-0096
Shifan ZhuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Jing MaCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Mingyue ZuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Jin YangNorthern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, China.
Fan XuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Linwei DaiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Dandan LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Yanhong WangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Xinjun ZhangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Siyang HuangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0003-1452-1299
Jinjun XuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhiming PanCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Jianping TaoCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0003-4669-9470
Zhaofeng HouCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0003-3680-6156

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Energy MetabolismMitochondriaPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionTOR Serine-Threonine KinasesToxoplasmaAnimalsCell LineGlycolysisHomeostasisMetabolic ReprogrammingOxidative PhosphorylationPhosphatidylinositol 3-KinaseSwinePhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinasesenergy metabolic reprogrammingLY294002mitochondrial dynamicsPI3K/Akt/mTORToxoplasma gondii

Identifiers

PMID41427835
PMCPMC12889155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.