Evidence map›Paper›PMID 41427789›Full record

ArticleEmerging microbes & infections2026

The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs.

Yao Li, Yingnan Liu, Zhuyun Sun, Zhenhua Xie, Chuanwen Tian, Rongrong Wang, Jun Gao, Maomao Wang, Jingyi Liu, Heng Wang and 5 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yao LiChinese Academy of Agricultural Sciences, Shanghai Veterinary Research Institute, Shanghai, People's Republic of China.
Yingnan LiuState Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
Zhuyun SunChinese Academy of Agricultural Sciences, Shanghai Veterinary Research Institute, Shanghai, People's Republic of China.
Zhenhua XieThe Spirit Jinyu Biological Pharmaceutical Co. Ltd., Hohhot, People's Republic of China.
Chuanwen TianChinese Academy of Agricultural Sciences, Shanghai Veterinary Research Institute, Shanghai, People's Republic of China.
Rongrong WangChinese Academy of Agricultural Sciences, Shanghai Veterinary Research Institute, Shanghai, People's Republic of China.
Jun GaoThe Spirit Jinyu Biological Pharmaceutical Co. Ltd., Hohhot, People's Republic of China.
Maomao WangThe Spirit Jinyu Biological Pharmaceutical Co. Ltd., Hohhot, People's Republic of China.
Jingyi LiuChinese Academy of Agricultural Sciences, Shanghai Veterinary Research Institute, Shanghai, People's Republic of China.
Heng WangGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, People's Republic of China.
Guihong ZhangGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, People's Republic of China.
Jie LiThe Spirit Jinyu Biological Pharmaceutical Co. Ltd., Hohhot, People's Republic of China.
Dongdong DiThe Spirit Jinyu Biological Pharmaceutical Co. Ltd., Hohhot, People's Republic of China.
Lang GongGuangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, People's Republic of China.
Hongjun ChenChinese Academy of Agricultural Sciences, Shanghai Veterinary Research Institute, Shanghai, People's Republic of China.ORCID 0000-0002-7254-7596

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control. In this study, we used the Chinese I/II genomic recombinant virulent strain ASFV-HN10005 (ASFV-HN) to construct two gene-deleted viruses. ASFV-HNΔMGF lacks the

Indexed as

African Swine FeverAfrican Swine Fever VirusGene DeletionViral ProteinsViral VaccinesAnimalsGenotypeSwineVaccines, AttenuatedVirulenceVaccines, AttenuatedViral ProteinsViral VaccinesAfrican swine fever viruscross-protectionEP402Rgene deletiongenotype I and II

Identifiers

PMID41427789
PMCPMC12798666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.