Evidence map›Paper›PMID 41427617›Full record

ArticleFuture science OA2026

Cancer and dementia incidence are strongly correlated worldwide: evidence from cross-national regression analyses.

Wenpeng You, Brendon J Coventry, Maciej Henneberg

Abstract read
In one paragraph

Article in Future science OA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wenpeng YouBiological Anthropology and Comparative Anatomy Unit, School of Biomedicine, the University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0002-6229-1064
Brendon J CoventryDiscipline of Surgery, University of Adelaide, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID 0000-0002-3596-7735
Maciej HennebergBiological Anthropology and Comparative Anatomy Unit, School of Biomedicine, the University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0003-1941-2286

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer and dementia are two major global health challenges influenced by population aging and socioeconomic transitions. Both impose substantial burdens, yet their relationship at the population level is insufficiently explored. This study investigated the global association between cancer incidence and dementia incidence, while accounting for developmental, demographic, and healthcare-related factors.

methodsData were obtained from the Institute for Health Metrics and Evaluation. Covariates included economic affluence, urbanization, reduced selection opportunity, and life expectancy e(60). Analyses across 204 countries employed correlations, partial correlations, principal component analysis, and multiple linear regression (enter and stepwise). Subgroup analyses were stratified by income level, development status, WHO regions, and geopolitical groupings.

resultsCancer incidence was strongly correlated with dementia incidence worldwide (r = 0.873;

conclusionCancer incidence is a dominant independent predictor of dementia incidence globally, surpassing traditional factors. Findings highlight shared determinants and emphasize the importance of integrated chronic disease strategies, especially in low-resource settings.

Indexed as

Alzheimer diseaseCancer epidemiologydementia epidemiologyecological studiesglobal healthlife expectancysocioeconomic factors

Identifiers

PMID41427617
PMCPMC12724431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.