Evidence map›Paper›PMID 41427573›Full record

ArticlePacing and clinical electrophysiology : PACE2026

Safety Outcomes of Hybrid Open Chest Transvenous Lead Extraction: A Multicenter Experience.

Nadeev Wijesuriya, Helena Lytton Cobbold, Keisha Kellman, Nikolaos Vogiatzakis, Felicity De Vere, Sandra Howell, Alphonsus Liew, Jonathan M Behar, Paolo Bosco, Gianluca Lucchese and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pacing and clinical electrophysiology : PACE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nadeev WijesuriyaKing's College London, London, UK.ORCID 0000-0001-7893-0708
Helena Lytton CobboldGuy's and St Thomas's NHS Foundation Trust, London, UK.
Keisha KellmanGuy's and St Thomas's NHS Foundation Trust, London, UK.
Nikolaos VogiatzakisGuy's and St Thomas's NHS Foundation Trust, London, UK.
Felicity De VereKing's College London, London, UK.
Sandra HowellKing's College London, London, UK.
Alphonsus LiewKing's College London, London, UK.ORCID 0000-0003-0098-4129
Jonathan M BeharKing's College London, London, UK.
Paolo BoscoGuy's and St Thomas's NHS Foundation Trust, London, UK.
Gianluca LuccheseGuy's and St Thomas's NHS Foundation Trust, London, UK.
Vias MarkidesGuy's and St Thomas's NHS Foundation Trust, London, UK.
Neil R GrubbEdinburgh Heart Centre, Edinburgh, UK.
Vishal MehtaKing's College London, London, UK.
Steven A NiedererImperial College London, London, UK.ORCID 0000-0002-4612-6982
Tom WongKing's College London, London, UK.
Christopher A RinaldiKing's College London, London, UK.

Funding

British Heart FoundationCentre For Medical Engineering, King's College LondonEuropean Research Council
6 · The paper itself

Abstract

backgroundHybrid open chest transvenous lead extraction (TLE), combining surgical and endovascular techniques, may be utilized in patients requiring concomitant cardiac surgery or with high-risk features for endovascular extraction. Outcome data in this population remains sparse.

aimsTo evaluate procedural outcomes and identify predictors of complications in patients undergoing elective hybrid open chest TLE.

methodsA retrospective multicenter cohort study was conducted, including 40 patients between 2017 and 2025 across three UK tertiary centers. Patients undergoing emergency surgical conversion were excluded. Baseline, procedural, and outcome data were collected. Primary outcomes were in-hospital mortality and complications, graded using a modified Delphi classification. Logistic regression was used to identify predictors of any or severe (Delphi grade ≥3) complications.

resultsThe mean age was 61.9 ± 17 years; 62.5% were male. Median lead dwell time was 10.5 years. The indication was infection in 65% of cases. Concomitant valve intervention was performed in 77.5% of cases. Clinical procedural success was 97.5%. In-hospital mortality was 2.5%, with a rate of severe complications of 15%, and an overall complication rate of 37.5%. Multivariable analysis identified chronic lung disease as an independent predictor of severe complications (OR 102.2, p = 0.03). Atrial fibrillation was an independent predictor of any complication (OR 5.83, p = 0.04), driven primarily by post-procedure rhythm intervention. Lead dwell time and EROS classification were not associated with adverse outcomes.

conclusionHybrid open chest TLE demonstrates high procedural success and despite significant morbidity, has acceptable mortality rates. Chronic lung disease independently predicts complications and should guide patient selection and perioperative planning.

Indexed as

Defibrillators, ImplantableDevice RemovalPacemaker, ArtificialAgedDevice Lead ExtractionFemaleHospital MortalityHumansMaleMiddle AgedPostoperative ComplicationsRetrospective Studiescardiac implantable electronic devicecardiac surgeryextraction

Identifiers

PMID41427573
PMCPMC12958016

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