Evidence map›Paper›PMID 41427555›Full record

ArticleTransfusion2026

Provider perceptions of indications for red blood cell transfusion.

Aishwarya Katiki, Selwyn Rogers, Ryan Boudreau, David Meltzer, Micah Prochaska

Abstract read
In one paragraph

Article in Transfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aishwarya KatikiPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.
Selwyn RogersSection of Trauma and Acute Care Surgery, Department of Surgery, University of Chicago, Chicago, Illinois, USA.
Ryan BoudreauSection of Trauma and Acute Care Surgery, Department of Surgery, University of Chicago, Chicago, Illinois, USA.
David MeltzerSection of Hospital Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Micah ProchaskaPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.

Funding

Summer Program to Increase Heart, Lung, and Blood Biomedical ResearchR25HL096383 · NHLBI · UNIVERSITY OF CHICAGO · PI CHRISTOPHER O OLOPADE, William F Parker · 2009 to 2026
$2.1M
The Effect of Red Blood Cell Transfusion on Fatigue, Activity and Fatigability in Hospitalized Patients with AnemiaK23HL140132 · NHLBI · UNIVERSITY OF CHICAGO · PI PROCHASKA, MICAH THOMAS · 2018 to 2022
$736k
Development and Validation of a Computerized Adaptive Test of FatigabilityR43AG086081 · NIA · ADAPTIVE TESTING TECHNOLOGIES · PI COHEN, YEHUDA, PROCHASKA, MICAH THOMAS · 2024 to 2024
$345k
NHLBI NIH HHS K23 HL140132NHLBI NIH HHS R25 HL096383NIA NIH HHS R43 AG086081NIH HHS NHLBI K23HL140132NIH HHS NHLBI R25HL096383-13NIH HHS NIA R43 AG086081
6 · The paper itself

Abstract

backgroundGuidelines for red blood cell transfusion recommend incorporating patient factors and clinical context beyond hemoglobin (Hb) levels. However, limited data exist on which factors clinicians consider important. Understanding these decision-making elements can clarify how guidelines are applied and inform future research. This study aimed to identify and prioritize factors that influence transfusion decisions among inpatient clinicians. STUDY DESIGN AND

methodsInpatient clinicians who are high utilizers of transfusion were administered a survey and asked to rate the importance of 30 decision-making factors using a 3-point Likert scale (very, somewhat, not important). Additional questions addressed transfusion practices and anemia management using a 5-point Likert scale (very much disagree to very much agree). Descriptive statistics were used to characterize study participants and survey responses, and regression models explored associations between responses and participant characteristics.

resultsOf 95 eligible clinicians, 85 (89%) completed the survey. Only 7 of the 30 factors were rated as "very important" by more than 66% of respondents; 5 of these were Hb-related. Importance assigned to other non-Hb-related factors varied. Most clinicians (85%) do believe that anemia can result in significant adverse consequences. Most clinicians further believe that restrictive transfusion is standard of care (88%) and optimal (68%), but also that transfusion decisions need to incorporate factors other than a patient's Hb level (84%) at the same time.

conclusionDespite guidelines suggestions, there is a lack of consensus on what clinical factors beyond Hb clinicians believe are important in making transfusion decisions.

Indexed as

Attitude of Health PersonnelErythrocyte TransfusionAdultAnemiaClinical Decision-MakingFemaleHemoglobinsHumansMaleMiddle AgedPractice Patterns, Physicians'Surveys and QuestionnairesHemoglobinsRBC transfusiontransfusion practices (adult)transfusion practices (surgical)

Identifiers

PMID41427555
PMCPMC12902728

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.