Evidence map›Paper›PMID 41427474›Full record

ArticleEnvironmental toxicology2026

Evaluation of the Intergenerational Effects of Arecoline on Aedes aegypti via Acute Exposure and Its Role in Inducing the Leg Deformities Involved in Chitin Synthesis Inhibition.

Yuejie Wu, Fei Wang, Longxiang Gao, Yunfei Zhang, Lanying Wang, Yanping Luo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuejie WuSchool of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Fei WangSchool of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Longxiang GaoSchool of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Yunfei ZhangSchool of Tropical Agriculture and Forestry, Hainan University, Haikou, China.ORCID https://orcid.org/0009-0009-2271-9546
Lanying WangSchool of Tropical Agriculture and Forestry, Hainan University, Haikou, China.
Yanping LuoSchool of Tropical Agriculture and Forestry, Hainan University, Haikou, China.ORCID https://orcid.org/0000-0002-2184-4291

Funding

Hainan Province Science and technology species fund ZDKJ2021041National Natural Science Foundation of China 31860513National Natural Science Foundation of China 32260685
6 · The paper itself

Abstract

Arecoline is a major active alkaloid in Areca catechu L. Currently, its biological toxicity has been extensively explored using multiple models, such as cell lines, animal embryos and representatives of rodent and non-rodent species. However, the intergenerational impacts of this compound on aquatic invertebrate species remain still unclear. Thus, in this study, using Aedes aegypti as the model insect, we evaluated the toxicity of arecoline to the larvae and its subsequent effects on the developmental parameters of the parental (F

Indexed as

AedesArecolineChitinWater Pollutants, ChemicalAnimalsExtremitiesFemaleLarvaArecolineChitinWater Pollutants, Chemicalacute exposure toxicityAedes aegyptiarecolinechitin synthesis suppressionintergenerational impactsleg deformities

Identifiers

PMID41427474
PMCPMC13436144

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.