ArticleGMS ophthalmology cases2025
Results of contralateral Athens and decentered individualized sphero-cylindrical (DISC) protocols for keratoconus management.
Article in GMS ophthalmology cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To present the results of two different surgical procedures, decentered individualized sphero-cylindrical protocol (DISC protocol) and Athens protocol, performed on a 34-year-old patient after being diagnosed with keratoconus in both eyes. Observation: The patient's left eye was subjected to the Athens protocol (phototherapeutic keratectomy (PTK) + partial topo-guided photorefractive keratectomy (TG-PRK) + corneal cross-linking (CXL)). In contrast, the patient's right eye was subjected to the DISC protocol (PTK + DISC excimer ablation + CXL). After administration of topical anesthetic, the patient was subjected to PTK of the central 7 mm optical zone with 50 µm depth of epithelial ablation. After excimer laser ablation in both eyes, riboflavin 0.1% solution was applied topically every 2 minutes for 20 minutes. This was followed by five cycles of 5-minute-long irradiation (for 25 minutes) using a UVA 370 nm at 3.0 mW/cm Conclusion and importance: DISC protocol is a novel approach, with the potential to become a promising strategy for slowing the progression of keratoconus and recovering uncorrected visual abilities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.