ArticleFrontiers in cellular neuroscience2025
Long-term low-dose aspirin promotes laser-induced choroidal neovascularization through suppressing TSP-1 expression.
Article in Frontiers in cellular neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Exercise-induced neuropeptidergic and neurochemical neuroadaptation in stress regulation and emotional disorders.Acta neurologica Belgica · 2026Review
- Choroid plexus enlargement correlates with cognitive dysfunction and disease progression in Moyamoya disease.Neurosurgical review · 2025Article
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Authors and funding
13 authors.
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Abstract
Purpose: To investigate the impact of low-dose, long-term aspirin use on neovascular age-related macular degeneration (nAMD). Methods: Adult C57BL/6J or Thbs-1 Results: Aspirin treatment did not affect circulating immune cell profiles in normal mice but significantly increased CD11b Conclusion: Low-dose long-term aspirin use promoted the severity of laser-induced CNV by down-regulating TSP-1. Lower serum levels of TSP-1 may be a risk factor for nAMD. The long-term ocular safety of aspirin should be validated in prospective cohorts.
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