ArticlebioRxiv : the preprint server for biology2025
Vaccine-induced antigenic drift of a human-origin H3N2 Influenza A virus in swine alters glycan binding and sialic acid avidity.
Matias Cardenas, Pradeep Chopra, Brianna Cowan, C Joaquin Caceres, Tavis K Anderson, Amy L Baker, Daniel R Perez, Geert-Jan Boons, Daniela S Rajao
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
9 authors.
Matias CardenasDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Pradeep ChopraComplex Carbohydrate and Research Center, University of Georgia, Athens, GA, USA.
Brianna CowanDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
C Joaquin CaceresDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Tavis K AndersonNational Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, USA.ORCID 0000-0002-3138-5535 Amy L BakerNational Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA, USA.ORCID 0000-0002-4953-7285 Daniel R PerezDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.ORCID 0000-0002-6569-5689 Geert-Jan BoonsComplex Carbohydrate and Research Center, University of Georgia, Athens, GA, USA.
Daniela S RajaoDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.ORCID 0000-0002-0772-0065 Funding
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00014 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GARCIA-SASTRE, ADOLFO · 2021 to 2025
$62.6MNIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00015 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HENSLEY, SCOTT · 2021 to 2025
$50.7MAutomated chemo-enzymatic synthesis of N-glycans for host-pathogen interactionsR01AI165692 · NIAID · UNIVERSITY OF GEORGIA · PI BOONS, GEERT-JAN · 2022 to 2025
$2.2MNIAID NIH HHS 75N93021C00014NIAID NIH HHS 75N93021C00015NIAID NIH HHS R01 AI165692
6 · The paper itselfAbstract
Interspecies transmission of human influenza A viruses (FLUAV) to swine occurs frequently, yet the molecular factors driving adaptation remain poorly understood. Here we investigated how vaccine-induced immunity shapes the evolution of a human-origin H3N2 virus in pigs using an
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PMCPMC12712928
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